Griseofulvin-13C,d3

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Griseofulvin-13C,d3 

Griseofulvin-13C,d3 是一种 13C- 和氘代标记的 Griseofulvin。Griseofulvin(Gris-PEG; Grifulvin)是一抗真菌感染试剂。

Griseofulvin-13C,d3

Griseofulvin-13C,d3 Chemical Structure

CAS No. : 1329612-29-4

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生物活性

Griseofulvin-13C,d3 is the 13C- and deuterium labeled.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[73].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

356.78

Formula

C1613CH14D3ClO6

CAS 号

1329612-29-4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

    [2]. Brilhante RSN, et al. In vitro activity of azole derivatives and griseofulvin against planktonic and biofilm growth of clinical isolates of dermatophytes. Mycoses. 2018 Jul;61(7):449-454.

    [3]. Schmeel LC, et al. Griseofulvin Efficiently Induces Apoptosis in In Vitro Treatment of Lymphoma and Multiple Myeloma. Anticancer Res. 2017 May;37(5):2289-2295.

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