KRAS G12C inhibitor 43

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

KRAS G12C inhibitor 43 

KRAS G12C inhibitor 43 (compound 59) 是一种有效 KRAS G12C 抑制剂。KRAS G12C inhibitor 43 对 H358, A549, HCC 细胞具有抗迁移和抗增殖活性，IC50s 分别为 0.001-1 µM, >1 µM, >1 µM。

KRAS G12C inhibitor 43

KRAS G12C inhibitor 43 Chemical Structure

CAS No. : 2648808-69-7

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生物活性

KRAS G12C inhibitor 43 (compound 59) is a potent KRAS G12C inhibitor. KRAS G12C inhibitor 43 shows antimigration and anti-proliferative activity with IC50s of 0.001-1 µM, >1 µM, >1 µM for H358, A549, HCC cells ,respectively[1].

IC50 & Target[1]

KRas G12C

 

分子量

577.68

Formula

C33H35N7O3
CAS 号

2648808-69-7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Xu Wei, et al. Pyridopyrimidine kras g12c mutant protein inhibitor. WO2021139678A1.

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