EGFR-IN-54

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

EGFR-IN-54 

EGFR-IN-54 (Compound 3c) 是一种有效的 EGFR 抑制剂，IC50 值为 1.623 µM。EGFR-IN-54 对癌细胞具有毒性。

EGFR-IN-54

EGFR-IN-54 Chemical Structure

CAS No. : 2418549-30-9

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生物活性

EGFR-IN-54 (Compound 3c) is a potent EGFR inhibitor with an IC50 of 1.623 µM. EGFR-IN-54 shows cytotoxic activity against cancer cell lines[1].

IC50 & Target

EGFR

1.623 μM (IC50)

分子量

434.51

Formula

C17H14N4O4S3
CAS 号

2418549-30-9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Abbas SY, et al. Synthesis and anticancer activity of thiourea derivatives bearing a benzodioxole moiety with EGFR inhibitory activity, apoptosis assay and molecular docking study. Eur J Med Chem. 2020 Jul 15;198:112363.

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