ANO1-IN-2

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

ANO1-IN-2 

ANO1-IN-2 (Compound 10q) 是一种选择性的 ANO1 通道阻断剂，对 ANO1 和 ANO2 的 IC50 值分别为 1.75 μM 和 7.43 μM。ANO1-IN-2 强烈抑制胶质瘤细胞的增殖。

ANO1-IN-2

ANO1-IN-2 Chemical Structure

CAS No. : 637314-12-6

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生物活性

ANO1-IN-2 (Compound 10q) is a selective ANO1 channel blocker with an IC50 of 1.75 μM and 7.43 μM against ANO1 and ANO2, respectively. ANO1-IN-2 suppresses strongly proliferation of glioblastoma cells[1].

IC50 & Target

IC50: 1.75 μM (ANO1), 7.43 μM (ANO2)[1]
体外研究
(In Vitro)

ANO1-IN-2 (Compound 10q) (10 μM) significantly suppresses migration and invasion of U251 cells[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

379.88

Formula

C16H14ClN3O2S2
CAS 号

637314-12-6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Choi SH, et al. Anti-glioma effects of 2-aminothiophene-3-carboxamide derivatives, ANO1 channel blockers. Eur J Med Chem. 2020 Dec 15;208:112688.

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