Antitumor agent-64

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Antitumor agent-64 

Antitumor agent-64 (Compound 8d) 是薯蓣皂苷元衍生物。Antitumor agent-64 对 A549 细胞系表现出有效的细胞毒活性。Antitumor agent-64 通过线粒体相关通路诱导 A549 细胞凋亡 (apoptosis)。

Antitumor agent-64

Antitumor agent-64 Chemical Structure

CAS No. : 2396562-55-1

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生物活性

Antitumor agent-64 (Compound 8d) is a diosgenin derivative. Antitumor agent-64 exhibits potent cytotoxic activity against A549 cell line. Antitumor agent-64 induces A549 cells apoptosis via the mitochondria-related pathway[1].

分子量

589.83

Formula

C35H47N3O3S
CAS 号

2396562-55-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Zhang J, et al. Novel diosgenin derivatives containing 1,3,4-oxadiazole/thiadiazole moieties as potential antitumor agents: Design, synthesis and cytotoxic evaluation. Eur J Med Chem. 2020 Jan 15;186:111897.

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