Vibsanin A

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Vibsanin A 

Vibsanin A 是一种蛋白激酶 C (PKC) 激活剂,对人类癌细胞系具有抗增殖活性。Vibsanin A 也是一种 HSP90 抑制剂。

Vibsanin A Vibsanin A

Vibsanin A Chemical Structure

CAS No. : 72506-14-0

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生物活性

Vibsanin A, a protein kinase C (PKC) activator, exhibits anti-proliferative activity against human cancer cell lines. Vibsanin A is also a HSP90 inhibitor[1].

分子量

402.57

Formula

C25H38O4

CAS 号

72506-14-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Miura K, et, al. Identification of vibsanin A analog as a novel HSP90 inhibitor. Bioorg Med Chem. 2020 Jan 15;28(2):115253.

    [2]. Shen X, et, al. Vibsanin A sensitizes human acute myeloid leukemia cells to tyrosine kinase inhibitor-induced myeloid differentiation via activation of PKC and upregulation of Lyn. Biochem Biophys Res Commun. 2018 Jul 7;502(1):110-115.

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