AS 1411(Synonyms: AGRO-100)

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AS 1411 (Synonyms: AGRO-100)

AS1411是一种靶向核仁素的核酸适配体，具有抗肿瘤的作用。

AS 1411(Synonyms: AGRO-100)

AS 1411 Chemical Structure

CAS No. : 301636-59-9

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生物活性

AS1411 is a quadruplex-forming oligonucleotide aptamer that targets nucleolin. It has anti-tumor activity.

CAS 号

301636-59-9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Teng Y, Girvan AC, Casson LK, et al. AS1411 alters the localization of a complex containing protein arginine methyltransferase 5 and nucleolin. Cancer Res. 2007;67(21):10491-10500.

    [2]. Soundararajan S, Chen W, Spicer EK, Courtenay-Luck N, Fernandes DJ. The nucleolin targeting aptamer AS1411 destabilizes Bcl-2 messenger RNA in human breast cancer cells. Cancer Res. 2008;68(7):2358-2365.

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