Tiragolumab

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Tiragolumab 

Tiragolumab 是一种与 T 细胞免疫球蛋白和 ITIM 结构域 (TIGIT) 结合的免疫检查点抑制剂。Tiragolumab 单独或与 PD-L1 抑制剂 Atezolizumab 联合使用,可能对多种实体恶性肿瘤有效,尤其是非小细胞肺癌。

Tiragolumab

Tiragolumab Chemical Structure

CAS No. : 1918185-84-8

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生物活性

Tiragolumab is an immune checkpoint inhibitor binding to T-cell immunoglobulin and ITIM domain (TIGIT). Tiragolumab, alone or in combination with the PD-L1 inhibitor Atezolizumab, may be effective against multiple solid malignancies-most notably non-small cell lung cancer[1][2].

CAS 号

1918185-84-8

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Mohammed Sqalli Houssaini, et al. Advances in the management of non-small cell lung cancer (NSCLC): A new practice changing data from asco 2020 annual meeting. Cancer Treat Res Commun. 2020;25:100239.

    [2]. Tiragolumab Impresses in Multiple Trials. Cancer Discov. 2020 Aug;10(8):1086-1087.

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