Mosunetuzumab(Synonyms: BTCT-4465A)

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Mosunetuzumab (Synonyms: BTCT-4465A)

Mosunetuzumab (BTCT-4465A) 是一种人源化、基于免疫球蛋白 G1 的双特异性抗体,靶向 CD20 (B 细胞) 和 CD3 (T 细胞)。Mosunetuzumab 重定向 T 细胞以接合和消除恶性 B 细胞,可用于研究复发或难治性 (R/R) B 细胞非霍奇金淋巴瘤 (B-NHL)。

Mosunetuzumab(Synonyms: BTCT-4465A)

Mosunetuzumab Chemical Structure

CAS No. : 1905409-39-3

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生物活性

Mosunetuzumab (BTCT-4465A) is a humanized, immunoglobulin G1-based bispecific antibody targeting CD20 (B cells) and CD3 (T cells). Mosunetuzumab redirects T cells to engage and eliminate malignant B cells and can be used for the research of relapsed or refractory (R/R) B-cell non-Hodgkin lymphomas (B-NHLs)[1].

CAS 号

1905409-39-3

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Lihua E Budde, et al. Single-Agent Mosunetuzumab Shows Durable Complete Responses in Patients With Relapsed or Refractory B-Cell Lymphomas: Phase I Dose-Escalation Study. J Clin Oncol. 2022 Feb 10;40(5):481-491.

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