二硬脂酰基磷脂酰乙醇胺 PEG 胺, DSPE-PEG-NH2

DSPE-PEG(2000)胺可用于：
生成单壁碳纳米管(SWNT)磷脂-聚乙二醇-叶酸偶联物
制备聚乙二醇(PEGylated)磁性纳米颗粒脂质体
制备脂质体，用于肌融合外结构域的破坏研究

DSPE PEG Amine (DSPE-PEG-NH2) is one of  reactive phospholipid PEG reagents that have a reactive primary amine group on one PEG terminus. DSPE (1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine) is a saturated 18C phospholipid commonly used in liposome synthesis.  Polyethylene glycol (PEG) conjugated DSPE has both hydrophilicity and hydrophobility property that is useful for drug delivery, gene transfection and biomolecule modification. Pegylation of phospholipids significantly improves the blood circulation time and stability for encapsulated drugs. Amine functionalized DSPE PEG allows further modification of PEG lipid via its reactive amino group.

DSPE-PEG(2000) Amine has been used:
for the generation of single-walled carbon nanotubes (SWNTs) phospholipid-polyethylene glycol-folic acid conjugate
in the preparation of polyethylene glycol (PEGylated) magnetic nanoparticles based liposomes
in the preparation of liposomes for myomerger ectodomain based disruption studies

application：

Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.