生物活性分子抑制剂 特异性抑制剂 激动剂 化合物库 重组蛋白 Nexturastat A 纯度: 98.49%
Nexturastat A是HDAC6高度选择性抑制剂,IC50为5 nM,对其它HDAC亚型无抑制性。
Nexturastat A Chemical Structure
CAS No. : 1403783-31-2
规格 | 价格 | 是否有货 | 数量 |
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10 mM * 1 mL in DMSO | ¥1727 | In-stock | |
1 mg | ¥780 | In-stock | |
5 mg | ¥2300 | In-stock | |
10 mg | ¥3900 | In-stock | |
50 mg | ¥9900 | In-stock | |
100 mg | ¥16000 | In-stock | |
200 mg | 询价 | ||
500 mg | 询价 |
* Please select Quantity before adding items.
Nexturastat A 相关产品
•相关化合物库:
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生物活性 |
Nexturastat A is a potent and selective HDAC6 inhibitor with IC50 of 5 nM; no inhibition on other HDAC forms. IC50 value: 5 nM [1] Target: HDAC6 inhibitor Nexturastat A displayed low micromolar activity compared to the low nanomolar activity against HDAC6. Moreover, it also demonstrated high levels of selective inhibition against members of the related Class 2 HDAC isozymes reaching >1000-fold selective in some cases. Compared to the pan-selective HDACI LBH589, Nexturastat A is approximately 100-fold less potent in inducing murine B16 melanoma cell death. |
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IC50 & Target[1] |
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分子量 |
341.40 |
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Formula |
C19H23N3O3 |
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CAS 号 |
1403783-31-2 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 |
In Vitro:
DMSO : ≥ 56 mg/mL (164.03 mM) * “≥” means soluble, but saturation unknown. 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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