上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
CCR6 inhibitor 1 纯度: 99.87%
CCR6 inhibitor 1 是一种有效、选择性的 CCR6 抑制剂,对猴子和人 CCR6 的 IC50 值分别为 0.45 和 6 nM,对其选择性远高于人 CCR1 (IC50,> 30000 nM) 和 CCR7 (IC50,9400 nM)。CCR6 inhibitor 1 显著抑制 ERK 磷酸化。可用于自身免疫病和癌症的研究。
CCR6 inhibitor 1 Chemical Structure
CAS No. : 2437547-04-9
规格 | 价格 | 是否有货 | 数量 |
---|---|---|---|
10 mM * 1 mL in DMSO | ¥4995 | In-stock | |
5 mg | ¥4500 | In-stock | |
10 mg | ¥7500 | In-stock | |
50 mg | ¥19500 | In-stock | |
100 mg | ¥33000 | In-stock | |
200 mg | 询价 | ||
500 mg | 询价 |
* Please select Quantity before adding items.
CCR6 inhibitor 1 相关产品
•相关化合物库:
- Bioactive Compound Library Plus
- GPCR/G Protein Compound Library
- Immunology/Inflammation Compound Library
- Anti-Cancer Compound Library
- Small Molecule Immuno-Oncology Compound Library
- Endocrinology Compound Library
- Targeted Diversity Library
生物活性 |
CCR6 inhibitor 1 is a potent and selective CCR6 inhibitor, with IC50s of 0.45 and 6 nM for monkey and human CCR6, much more selective at CCR6 over human CCR1 (IC50, > 30000 nM), and CCR7 (IC50, 9400 nM). CCR6 inhibitor 1 markedly blocks ERK phosphorylation. CCR6 inhibitor 1 is used in the research of autoimmune diseases and cancer[1]. |
||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
IC50 & Target[1] |
|
||||||||||||||||
体外研究 (In Vitro) |
CCR6 inhibitor 1 (Compound 35) inhibits L20-induced human B cell migration[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
||||||||||||||||
分子量 |
504.52 |
||||||||||||||||
Formula |
C24H23F3N4O3S |
||||||||||||||||
CAS 号 |
2437547-04-9 |
||||||||||||||||
运输条件 |
Room temperature in continental US; may vary elsewhere. |
||||||||||||||||
储存方式 |
|
||||||||||||||||
溶解性数据 |
In Vitro:
DMSO : ≥ 125 mg/mL (247.76 mM) * “≥” means soluble, but saturation unknown. 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
|
||||||||||||||||
参考文献 |
|
所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务