新金丝菌素
金链菌素的扩链类似物
98%
有货
基本信息
| 产品名称 | 新金丝菌素 |
|---|---|
| 英文名称 | Neoaureothin |
| 别名 | 新金黄素;2-甲氧基-3,5-二甲基-6-[(2R,4Z)-四氢-4- [(2E,4E,6E) -2,4,6-三甲基-7-(4-硝基苯基) -2 ,4,6-庚三烯-1-亚叉基]-2-呋喃基]-4H-吡喃-4-酮 |
| 英文别名 | Spectabilin |
| 规格或纯度 | 98% |
| 运输条件 | 超低温冰袋运输 |
一般描述
新金丝菌素是金链菌素的一种不寻常的链延长类似物。最初报道它是链霉菌中新抗霉素的共代谢物。据报道具有抗HIV和抗真菌活性。具有强大的杀线虫和抗肿瘤活性。新金霉素的两种光异构体，抗生素SNF4435C和D，已被确定为有效的免疫抑制剂。
Neoaureothin is an unusual chain-extended analogue of aureothin. It was first reported as a co-metabolite ofneoantimycin in Streptomyces orinoci. It has been reported to have anti-HIV and antifungal activity. Possesses potent nematocidal and antitumor activity. Two photo-isomers of neoaureothin, Antibiotics SNF4435C and D, have been identified as potent immunosuppressive agents.
相关属性
| CAS编号 | 28900-27-8 |
|---|---|
| 折光率 | n20D1.59 (Predicted) |
| 熔点 | 252.86° C (Predicted) |
| 沸点 | 660.71° C at 760 mmHg (Predicted) |
| 溶解性 | Soluble in DMSO, DMF, water (poor), ethanol, and methanol. |
| 储存温度 | -20°C储存 |
| 密度 | 1.20 g/cm3(Predicted) |
| 分子量 | 477.55 |
| 分子式 | C₂₈H₃₁NO₆ |
| 品牌 | Jinpan |
| Smiles | CC1=C(OC(=C(C1=O)C)OC)C2CC(=CC(=CC(=CC(=CC3=CC=C(C=C3)[N+](=O)[O-])C)C)C)CO2 |
| IC50 | NADH fumarate reductase: IC₅₀= 15 nM |
| 关联CAS | 59795-94-7 |
| PubChem CID | 6382650 |