莫西克汀
基本信息
| 产品名称 | 莫西克汀 |
|---|---|
| 英文名称 | Moxidectin |
| 别名 | 莫西克汀;莫西菌素 莫西丁克 |
| 英文别名 | ProHeart 6; CL301423; Cydectin |
| 规格或纯度 | 98% |
| 运输条件 | 超低温冰袋运输 |
| 生化机理 | Moxidectin is an orally active antihelminthic (antiparasitic) that targets parasite glutamate-gated chloride ion channels (GluCls). Moxidectin binding increases target GluCl permeability, resulting in influx of chloride ions and dysfunction of the excretory pore, flaccid paralysis, and death of the parasite through host response. |
一般描述
应用：
Moxidectin是驱虫剂，可用于预防和控制心丝虫和蛔虫。
Moxidectin is an anthelmintic drug which kills parasitic worms (helminths), and is used for the prevention and control of heartworm and intestinal worms. Moxidectin is a semisynthetic derivative of nemadectin, which is produced by fermentation by Streptomyces cyano-griseus. Moxidectin treats and controls some of the most common internal and external parasites by selectively binding to a parasite’s glutamate-gated chloride ion channels. These channels are vital to the function of invertebrate nerve and muscle cells; when moxidectin binds to the channels, it disrupts neurotransmission, resulting in paralysis and death of the parasite. Studies of moxidectin show the side effects vary by animal and may be affected by the product’s formulation, application method and dosage.
相关属性
| CAS编号 | 113507-06-5 |
|---|---|
| 敏感性 | 对热敏感 |
| 比旋光度 | 140° (C=1,CHCl₃) |
| 熔点 | 132 °C |
| 溶解性 | 128 mg/mL in Ethanol; ≥129.4 mg/mL in DMSO; ≥3.27 mg/mL in H2O with gentle warming and ultrasonic |
| 储存温度 | -20°C储存 |
| MDL号 | MFCD00866560 |
| 密度 | 1.23 |
| 分子量 | 639.82 |
| 分子式 | C37H53NO8 |
| 品牌 | Jinpan |