上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
Rotundic acid (Synonyms: 铁冬青酸) 纯度: 99.41%
Rotundic acid 是一种从圆形肠球菌 (I. rotunda) 中获得的三萜类化合物,可通过 AKT/mTOR 和 MAPK 途径在肝细胞癌中诱导 DNA 损伤和细胞凋亡。Rotundic acid 具有抗炎和保护心脏的能力。
Rotundic acid Chemical Structure
CAS No. : 20137-37-5
规格 | 价格 | 是否有货 | 数量 |
---|---|---|---|
5 mg | ¥1500 | In-stock | |
10 mg | ¥2500 | In-stock | |
50 mg | 询价 | ||
100 mg | 询价 |
* Please select Quantity before adding items.
Rotundic acid 相关产品
•相关化合物库:
- Natural Product Library Plus
- Bioactive Compound Library Plus
- Apoptosis Compound Library
- Immunology/Inflammation Compound Library
- Kinase Inhibitor Library
- MAPK Compound Library
- PI3K/Akt/mTOR Compound Library
- Stem Cell Signaling Compound Library
- Natural Product Library
- Anti-Cancer Compound Library
- Autophagy Compound Library
- Anti-Aging Compound Library
- Antioxidants Compound Library
- Differentiation Inducing Compound Library
- Reprogramming Compound Library
- Lipid Compound Library
- Oxygen Sensing Compound Library
- Anti-Cardiovascular Disease Compound Library
- Terpenoids Library
- Glycolysis Compound Library
- Pyroptosis Compound Library
- Cytoskeleton Compound Library
- Glutamine Metabolism Compound Library
- Traditional Chinese Medicine Monomer Library
- Anti-Breast Cancer Compound Library
- Anti-Lung Cancer Compound Library
- Anti-Pancreatic Cancer Compound Library
- Anti-Blood Cancer Compound Library
- Anti-Cancer Metabolism Compound Library
- Microbial Metabolite Library
- Neurodegenerative Disease-related Compound Library
- Anti-Obesity Compound Library
- Angiogenesis Related Compound Library
- Glucose Metabolism Compound Library
- Food-Sourced Compound Library
- Anti-Liver Cancer Compound Library
- Anti-Colorectal Cancer Compound Library
生物活性 |
Rotundic acid, a triterpenoid obtained from I. rotunda, induces DNA damage and cell apoptosis in hepatocellular carcinoma through AKT/mTOR and MAPK Pathways. Rotundic acid possesses anti-inflammatory and cardio-protective abilities[1]. |
||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
IC50 & Target[1] |
|
||||||||||||||||
分子量 |
488.70 |
||||||||||||||||
Formula |
C30H48O5 |
||||||||||||||||
CAS 号 |
20137-37-5 |
||||||||||||||||
中文名称 |
铁冬青酸 |
||||||||||||||||
运输条件 |
Room temperature in continental US; may vary elsewhere. |
||||||||||||||||
储存方式 |
4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
||||||||||||||||
溶解性数据 |
In Vitro:
DMSO : 100 mg/mL (204.62 mM; Need ultrasonic) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
|
||||||||||||||||
参考文献 |
|
所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务