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Maytansine (Synonyms: NSC 153858) 纯度: 99.50%
Maytansine 是一种高效的微管靶向化合物,可诱导有丝分裂阻滞并在亚纳摩尔浓度杀死肿瘤细胞。
Maytansine Chemical Structure
CAS No. : 35846-53-8
规格 | 价格 | 是否有货 | 数量 |
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5 mg | ¥4700 | In-stock | |
10 mg | ¥6200 | In-stock | |
20 mg | ¥10500 | In-stock | |
50 mg | 询价 | ||
100 mg | 询价 |
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Maytansine 相关产品
•相关化合物库:
- Drug Repurposing Compound Library Plus
- FDA-Approved Drug Library Plus
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- Cell Cycle/DNA Damage Compound Library
- FDA-Approved Drug Library
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- Anti-Aging Compound Library
- Drug Repurposing Compound Library
- Macrocyclic Compound Library
- Cytoskeleton Compound Library
- FDA Approved & Pharmacopeial Drug Library
- Anti-Lung Cancer Compound Library
生物活性 |
Maytansine is a highly potent microtubule-targeted compound that induces mitotic arrest and kills tumor cells at subnanomolar concentrations[1]. |
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体外研究 (In Vitro) |
Maytansine, at 6×10-8 M, irreversibly inhibits cell division in eggs of sea urchins and clams. Maytansine causes the disappearance of a mitotic apparatus or prevents one from forming if added at early stages. Maytansine inhibits in vitro polymerization of tubulin[2]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
692.20 |
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Formula |
C34H46ClN3O10 |
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CAS 号 |
35846-53-8 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 |
In Vitro:
DMSO : 100 mg/mL (144.47 mM; Need ultrasonic) 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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