Hydroxy-PEG1-(CH2)2-Boc

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Hydroxy-PEG1-(CH2)2-Boc  纯度: ≥95.0%

Hydroxy-PEG1-(CH2)2-Boc 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

Hydroxy-PEG1-(CH2)2-Boc

Hydroxy-PEG1-(CH2)2-Boc Chemical Structure

CAS No. : 671802-00-9

规格 价格 是否有货 数量
10 mM * 1 mL in Water ¥610 In-stock
100 mg ¥550 In-stock
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Hydroxy-PEG1-(CH2)2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

Alkyl/ether

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

190.24

Formula

C9H18O4

CAS 号

671802-00-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
In Vitro: 

H2O : 100 mg/mL (525.65 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 5.2565 mL 26.2826 mL 52.5652 mL
5 mM 1.0513 mL 5.2565 mL 10.5130 mL
10 mM 0.5257 mL 2.6283 mL 5.2565 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

参考文献
  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

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