Thymalfasin(Synonyms: 胸腺法新; Thymosin α1)

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Thymalfasin (Synonyms: 胸腺法新; Thymosin α1) 纯度: 99.83%

Thymalfasin (thymosin-alpha 1) 是一个免疫调节化合物，能够提高 Thl 的免疫应答。

Thymalfasin(Synonyms: 胸腺法新; Thymosin α1)

Thymalfasin Chemical Structure

CAS No. : 62304-98-7

规格 价格 是否有货 数量
500 μg ￥1000 In-stock
1 mg ￥1600 In-stock
5 mg ￥4900 In-stock
10 mg ￥8600 In-stock
50 mg   询价  
100 mg   询价  

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Thymalfasin 相关产品

•相关化合物库:

  • Drug Repurposing Compound Library Plus
  • FDA-Approved Drug Library Plus
  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

Thymalfasin is an immunomodulating agent able to enhance the Thl immune response.

体外研究
(In Vitro)

Thymalfasin has been shown to have efficacy in multiple experimental models of immune dysfunction, mainly, infectious diseases such as hepatitis (woodchuck) and influenza (mouse), and cancer such as melanoma (mouse) and colorectal carcinoma (rat) where thymalfasin has shown antitumor effects[2].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究
(In Vivo)

Thymalfasin has been shown to have efficacy in multiple experimental models of immune dysfunction, mainly, infectious diseases such as hepatitis (woodchuck) and influenza (mouse), and cancer such as melanoma (mouse) and colorectal carcinoma (rat) where thymalfasin has shown antitumor effects[2].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial

分子量

3108.28

Formula

C129H215N33O55
CAS 号

62304-98-7
Sequence

N-acetyl-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn
Sequence Shortening

Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN
中文名称

胸腺法新
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -80°C 2 years
-20°C 1 year
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
In Vitro: 

H2O : 0.3 mg/mL (0.10 mM; Need ultrasonic and warming)
参考文献

  • [1]. Lao X et al. A modified thymosin alpha 1 inhibits the growth of breast cancer both in vitro and in vivo: suppressment of cell proliferation, inducible cell apoptosis and enhancement of targeted anticancer effects. Apoptosis. 2015 Oct;20(10):1307-20.

    [2]. Sjogren MH et al. Thymalfasin: an immune system enhancer for the treatment of liver disease. J Gastroenterol Hepatol. 2004 Dec;19(12):S69-72.

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