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Psoralidin (Synonyms: 补骨脂定) 纯度: 99.90%
Psoralidin 是 COX-2 和 5-LOX 的双重抑制剂。具有抗癌,抗菌和抗炎作用。Psoralidin 显著下调 NOTCH1 信号传导。Psoralidin 还极大地诱导 ROS 产生。
Psoralidin Chemical Structure
CAS No. : 18642-23-4
规格 | 价格 | 是否有货 | 数量 |
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5 mg | ¥600 | In-stock | |
10 mg | ¥1080 | In-stock | |
50 mg | 询价 | ||
100 mg | 询价 |
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Psoralidin 相关产品
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生物活性 |
Psoralidin is a dual inhibitor of COX-2 and 5-LOX, regulates ionizing radiation (IR)-induced pulmonary inflammation.Anti-cancer, anti-bacterial, and anti-inflammatory properties[1]. Psoralidin significantly downregulates NOTCH1 signaling. Psoralidin also greatly induces ROS generation[2]. |
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IC50 & Target[1] |
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体外研究 (In Vitro) |
Three breast cancer cell (BCC)populations (ALDH– cells, ALDH+ cells, and commercial BSCSs) are sensitive to Psoralidin treatment (10, 15, 20, and 25 μM; 24 hours) with IC50s ranging from 18 to 21 μM; however, the MCF-12A cells were resistant to Psoralidin[2]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability Assay[2]
Apoptosis Analysis[2]
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体内研究 (In Vivo) |
Psoralidin (5 mg/kg) regulates expression of pro-inflammatory cytokines that play an important role in inflammatory diseasesin IR-irradiated lung of BALB/c mouse[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
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分子量 |
336.34 |
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Formula |
C20H16O5 |
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CAS 号 |
18642-23-4 |
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中文名称 |
补骨脂定;补骨脂次素 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 |
In Vitro:
DMSO : 50 mg/mL (148.66 mM; ultrasonic and warming and heat to 60°C) 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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