DBCO-Val-Cit-PABC-PNP

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DBCO-Val-Cit-PABC-PNP 

DBCO-Val-Cit-PABC-PNP 是一种可降解 (cleavable) 的 ADC linker,可用于合成抗体偶联药物 (ADC)。

DBCO-Val-Cit-PABC-PNP

DBCO-Val-Cit-PABC-PNP Chemical Structure

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生物活性

DBCO-Val-Cit-PABC-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Cleavable

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

859.92

Formula

C46H49N7O10

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

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