标签归档：dbco

DBCO PEG Acid, DBCO-PEG-COOH Cat. No. PG2-CADB-5k 5000 Da 20 mg修饰性聚乙二醇

发表于由
回复

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DBCO PEG Acid, DBCO-PEG-COOH

Cat. No. PG2-CADB-5k DBCO PEG Acid, DBCO-PEG-COOH Cat. No. PG2-CADB-5k 5000 Da 20 mg
Specification 5000 Da
Unit Size 20 mg
Price $385.00

Qty Add to Cart

DBCO PEG acid, MW 1000, 2000, 3400, 5000, 10000 Da:

Nanocs’ DBCO (dibenzocyclooctyne) PEG acid, DBCO-PEG-COOH, is a heterobifunctional reactive PEG derivative that can go Click Chemistry reaction without a need of any metal catalysts. The strain-promoted 1,3-dipolar cycloaddition of cyclooctynes and azides, also termed as the Cu-free click reaction, is a bioorthogonal reaction that enables the conjugation of two molecules in aqueous solution. DBCO PEG derivatives possess fast kinetics and stability in aqueous buffer. DBCO reagents can be used to label azide-modified biomolecules spontaneously without the need for toxic Cu catalysts. Carboxylic acid group, on the other hand, can be activated to react with amines, hydroxy and other functional groups.

Nanocs DBCO PEG acid features:

  • Appearance: Off-white solid or semi-solid depends on MW of PEG;
  • Solubility: Soluble in water, DMSO and chloroform;
  • Reactivity: DBCO reactive to azide group while acid group reactive to amine and hydroxy groups.

Copper-free Click reaction procedures:

  • Prepare the azide-containing reagents in reaction buffer.
  • Add DBCO reagents to azide containing reagents. Add 1 mol equivalent of limiting reagent to 1.5~3.0 mol equivalents of abundance reagent.
  • Incubate the reaction at room temperature for 2~4 hours or 2~12 hours at 4 0C.
  • Purify conjugates either by dialysis or size-exclusion chromatograph.

Storage Conditions:

  • Store at -20 0C, desiccate. Protect from light. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

DNP PEG DBCO Cat. No. PG2-DBDN-5k 5000 Da 5 mg修饰性聚乙二醇

发表于由
回复

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DNP PEG DBCO

Cat. No. PG2-DBDN-5k
Specification 5000 Da
Unit Size 5 mg
Price $385.00

Qty Add to Cart

DNP-PEG-DBCO, DBCO PEG 2,4-Dintrophenyl:

Product Information:

  • Form: Solid;
  • Color: Yellow;
  • Solubility: Soluble in water, DMSO, DMF;
  • Absorption: 360 nm;
  • Purity: >95%;
  • Reactive to: Azide;

Storage Conditions:

  • Store at -20 0C. Protect from light.

DBCO PEG Acid, DBCO-PEG-COOH Cat. No. PG2-CADB-3k 3400 Da 20 mg修饰性聚乙二醇

发表于由
回复

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DBCO PEG Acid, DBCO-PEG-COOH

Cat. No. PG2-CADB-3k DBCO PEG Acid, DBCO-PEG-COOH Cat. No. PG2-CADB-3k 3400 Da 20 mg
Specification 3400 Da
Unit Size 20 mg
Price $385.00

Qty Add to Cart

DBCO PEG acid, MW 1000, 2000, 3400, 5000, 10000 Da:

Nanocs’ DBCO (dibenzocyclooctyne) PEG acid, DBCO-PEG-COOH, is a heterobifunctional reactive PEG derivative that can go Click Chemistry reaction without a need of any metal catalysts. The strain-promoted 1,3-dipolar cycloaddition of cyclooctynes and azides, also termed as the Cu-free click reaction, is a bioorthogonal reaction that enables the conjugation of two molecules in aqueous solution. DBCO PEG derivatives possess fast kinetics and stability in aqueous buffer. DBCO reagents can be used to label azide-modified biomolecules spontaneously without the need for toxic Cu catalysts. Carboxylic acid group, on the other hand, can be activated to react with amines, hydroxy and other functional groups.

Nanocs DBCO PEG acid features:

  • Appearance: Off-white solid or semi-solid depends on MW of PEG;
  • Solubility: Soluble in water, DMSO and chloroform;
  • Reactivity: DBCO reactive to azide group while acid group reactive to amine and hydroxy groups.

Copper-free Click reaction procedures:

  • Prepare the azide-containing reagents in reaction buffer.
  • Add DBCO reagents to azide containing reagents. Add 1 mol equivalent of limiting reagent to 1.5~3.0 mol equivalents of abundance reagent.
  • Incubate the reaction at room temperature for 2~4 hours or 2~12 hours at 4 0C.
  • Purify conjugates either by dialysis or size-exclusion chromatograph.

Storage Conditions:

  • Store at -20 0C, desiccate. Protect from light. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

DBCO PEG Acid, DBCO-PEG-COOH Cat. No. PG2-CADB-2k 2000 Da 25 mg修饰性聚乙二醇

发表于由
回复

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DBCO PEG Acid, DBCO-PEG-COOH

Cat. No. PG2-CADB-2k DBCO PEG Acid, DBCO-PEG-COOH Cat. No. PG2-CADB-2k 2000 Da 25 mg
Specification 2000 Da
Unit Size 25 mg
Price $425.00

Qty Add to Cart

DBCO PEG acid, MW 1000, 2000, 3400, 5000, 10000 Da:

Nanocs’ DBCO (dibenzocyclooctyne) PEG acid, DBCO-PEG-COOH, is a heterobifunctional reactive PEG derivative that can go Click Chemistry reaction without a need of any metal catalysts. The strain-promoted 1,3-dipolar cycloaddition of cyclooctynes and azides, also termed as the Cu-free click reaction, is a bioorthogonal reaction that enables the conjugation of two molecules in aqueous solution. DBCO PEG derivatives possess fast kinetics and stability in aqueous buffer. DBCO reagents can be used to label azide-modified biomolecules spontaneously without the need for toxic Cu catalysts. Carboxylic acid group, on the other hand, can be activated to react with amines, hydroxy and other functional groups.

Nanocs DBCO PEG acid features:

  • Appearance: Off-white solid or semi-solid depends on MW of PEG;
  • Solubility: Soluble in water, DMSO and chloroform;
  • Reactivity: DBCO reactive to azide group while acid group reactive to amine and hydroxy groups.

Copper-free Click reaction procedures:

  • Prepare the azide-containing reagents in reaction buffer.
  • Add DBCO reagents to azide containing reagents. Add 1 mol equivalent of limiting reagent to 1.5~3.0 mol equivalents of abundance reagent.
  • Incubate the reaction at room temperature for 2~4 hours or 2~12 hours at 4 0C.
  • Purify conjugates either by dialysis or size-exclusion chromatograph.

Storage Conditions:

  • Store at -20 0C, desiccate. Protect from light. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

DBCO PEG NHS Cat. No. PG2-DBNS-5k 5000 Da 20 mg修饰性聚乙二醇

发表于由
回复

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DBCO PEG NHS

Cat. No. PG2-DBNS-5k DBCO PEG NHS Cat. No. PG2-DBNS-5k 5000 Da 20 mg
Specification 5000 Da
Unit Size 20 mg
Price $385.00

Qty Add to Cart

Description:

Dibenzocycolctyne (DBCO) PEG NHS derivatives can go Click Chemistry reaction without a need of any metal catalysts. The strain-promoted 1,3-dipolar cycloaddition of cyclooctynes and azides, also termed as the Cu-free click reaction, is a bioorthogonal reaction that enables the conjugation of two molecules in aqueous solution. DBCO PEG derivatives possess fast kinetics and stability in aqueous buffer. DBCO reagents can be used to label azide-modified biomolecules spontaneous without the need for toxic Cu catalysts. NHS group, on the other hand, can react with primary amine group at alkaline pH to form a stable amide bond. NHS funtionalized DBCO PEG thus can be easily attached to proteins, antibodies, peptides or small molecules to derive DBCO reactive moiety.

Physical Properties:

  • Light yellow solid;
  • Soluble in water, DMSO, etc.;

Copper-free Click reaction procedures:

  • Prepare the azide-containing reagents in reaction buffer.
  • Add DBCO reagents to azide containing reagents. Add 1 mol equivalent of limiting reagent to 1.5~3.0 mol equivalents of abundance reagent.
  • Incubate the reaction at room temperature for 2~4 hours or 2~12 hours at 4 0C.
  • Purify conjugates either by dialysis or size-exclusion chromatograph.

Storage Conditions:

  • Store at -20 0C, desiccate. Protect from light. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

DBCO PEG NHS Cat. No. PG2-DBNS-3k 3400 Da 20 mg修饰性聚乙二醇

发表于由
回复

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DBCO PEG NHS

Cat. No. PG2-DBNS-3k DBCO PEG NHS Cat. No. PG2-DBNS-3k 3400 Da 20 mg
Specification 3400 Da
Unit Size 20 mg
Price $385.00

Qty Add to Cart

Description:

Dibenzocycolctyne (DBCO) PEG NHS derivatives can go Click Chemistry reaction without a need of any metal catalysts. The strain-promoted 1,3-dipolar cycloaddition of cyclooctynes and azides, also termed as the Cu-free click reaction, is a bioorthogonal reaction that enables the conjugation of two molecules in aqueous solution. DBCO PEG derivatives possess fast kinetics and stability in aqueous buffer. DBCO reagents can be used to label azide-modified biomolecules spontaneous without the need for toxic Cu catalysts. NHS group, on the other hand, can react with primary amine group at alkaline pH to form a stable amide bond. NHS funtionalized DBCO PEG thus can be easily attached to proteins, antibodies, peptides or small molecules to derive DBCO reactive moiety.

Physical Properties:

  • Light yellow solid;
  • Soluble in water, DMSO, etc.;

Copper-free Click reaction procedures:

  • Prepare the azide-containing reagents in reaction buffer.
  • Add DBCO reagents to azide containing reagents. Add 1 mol equivalent of limiting reagent to 1.5~3.0 mol equivalents of abundance reagent.
  • Incubate the reaction at room temperature for 2~4 hours or 2~12 hours at 4 0C.
  • Purify conjugates either by dialysis or size-exclusion chromatograph.

Storage Conditions:

  • Store at -20 0C, desiccate. Protect from light. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

DBCO PEG NHS Cat. No. PG2-DBNS-2k 2000 Da 20 mg修饰性聚乙二醇

发表于由
回复

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DBCO PEG NHS

Cat. No. PG2-DBNS-2k DBCO PEG NHS Cat. No. PG2-DBNS-2k 2000 Da 20 mg
Specification 2000 Da
Unit Size 20 mg
Price $425.00

Qty Add to Cart

Description:

Dibenzocycolctyne (DBCO) PEG NHS derivatives can go Click Chemistry reaction without a need of any metal catalysts. The strain-promoted 1,3-dipolar cycloaddition of cyclooctynes and azides, also termed as the Cu-free click reaction, is a bioorthogonal reaction that enables the conjugation of two molecules in aqueous solution. DBCO PEG derivatives possess fast kinetics and stability in aqueous buffer. DBCO reagents can be used to label azide-modified biomolecules spontaneous without the need for toxic Cu catalysts. NHS group, on the other hand, can react with primary amine group at alkaline pH to form a stable amide bond. NHS funtionalized DBCO PEG thus can be easily attached to proteins, antibodies, peptides or small molecules to derive DBCO reactive moiety.

Physical Properties:

  • Light yellow solid;
  • Soluble in water, DMSO, etc.;

Copper-free Click reaction procedures:

  • Prepare the azide-containing reagents in reaction buffer.
  • Add DBCO reagents to azide containing reagents. Add 1 mol equivalent of limiting reagent to 1.5~3.0 mol equivalents of abundance reagent.
  • Incubate the reaction at room temperature for 2~4 hours or 2~12 hours at 4 0C.
  • Purify conjugates either by dialysis or size-exclusion chromatograph.

Storage Conditions:

  • Store at -20 0C, desiccate. Protect from light. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

DBCO PEG Maleimide, DBCO-PEG-Mal Cat. No. PG2-DBML-5k 5000 Da 20 mg修饰性聚乙二醇

发表于由
回复

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DBCO PEG Maleimide, DBCO-PEG-Mal

Cat. No. PG2-DBML-5k DBCO PEG Maleimide, DBCO-PEG-Mal Cat. No. PG2-DBML-5k 5000 Da 20 mg
Specification 5000 Da
Unit Size 20 mg
Price $385.00

Qty Add to Cart

Description:

Maleimide PEG DBCO (dibenzocycolctyne) is one of Nanocs DBCO PEG derivatives that can go Click Chemistry reaction without a need of any metal catalysts. The strain-promoted 1,3-dipolar cycloaddition of cyclooctynes and azides, also termed as the Cu-free click reaction, is a bioorthogonal reaction that enables the conjugation of two molecules in aqueous solution. DBCO PEG derivatives possess fast kinetics and stability in aqueous buffer. DBCO reagents can be used to label azide-modified biomolecules spontaneous without the need for toxic Cu catalysts. Meanwhile, maleimide group can react with sulfhydryl (Thoil) groups at pH 6.5-7.5 easily. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties:

  • White/off-white solid or viscous liquid depends on molecule weight;
  • Soluble in aqeous buffer and DMSO;

Copper-free Click reaction procedures:

  • Prepare the azide-containing reagents in reaction buffer.
  • Add DBCO reagents to azide containing reagents. Add 1 mol equivalent of limiting reagent to 1.5~3.0 mol equivalents of abundance reagent.
  • Incubate the reaction at room temperature for 2~4 hours or 2~12 hours at 4 0C.
  • Purify conjugates either by dialysis or size-exclusion chromatograph.

Storage Conditions:

  • Store at -20 0C. Desiccate. Protect from light. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

DBCO PEG Maleimide, DBCO-PEG-Mal Cat. No. PG2-DBML-3k 3400 Da 20 mg修饰性聚乙二醇

发表于由
回复

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DBCO PEG Maleimide, DBCO-PEG-Mal

Cat. No. PG2-DBML-3k DBCO PEG Maleimide, DBCO-PEG-Mal Cat. No. PG2-DBML-3k 3400 Da 20 mg
Specification 3400 Da
Unit Size 20 mg
Price $385.00

Qty Add to Cart

Description:

Maleimide PEG DBCO (dibenzocycolctyne) is one of Nanocs DBCO PEG derivatives that can go Click Chemistry reaction without a need of any metal catalysts. The strain-promoted 1,3-dipolar cycloaddition of cyclooctynes and azides, also termed as the Cu-free click reaction, is a bioorthogonal reaction that enables the conjugation of two molecules in aqueous solution. DBCO PEG derivatives possess fast kinetics and stability in aqueous buffer. DBCO reagents can be used to label azide-modified biomolecules spontaneous without the need for toxic Cu catalysts. Meanwhile, maleimide group can react with sulfhydryl (Thoil) groups at pH 6.5-7.5 easily. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties:

  • White/off-white solid or viscous liquid depends on molecule weight;
  • Soluble in aqeous buffer and DMSO;

Copper-free Click reaction procedures:

  • Prepare the azide-containing reagents in reaction buffer.
  • Add DBCO reagents to azide containing reagents. Add 1 mol equivalent of limiting reagent to 1.5~3.0 mol equivalents of abundance reagent.
  • Incubate the reaction at room temperature for 2~4 hours or 2~12 hours at 4 0C.
  • Purify conjugates either by dialysis or size-exclusion chromatograph.

Storage Conditions:

  • Store at -20 0C. Desiccate. Protect from light. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

DBCO PEG Maleimide, DBCO-PEG-Mal Cat. No. PG2-DBML-2k 2000 Da 20 mg修饰性聚乙二醇

发表于由
回复

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DBCO PEG Maleimide, DBCO-PEG-Mal

Cat. No. PG2-DBML-2k DBCO PEG Maleimide, DBCO-PEG-Mal Cat. No. PG2-DBML-2k 2000 Da 20 mg
Specification 2000 Da
Unit Size 20 mg
Price $425.00

Qty Add to Cart

Description:

Maleimide PEG DBCO (dibenzocycolctyne) is one of Nanocs DBCO PEG derivatives that can go Click Chemistry reaction without a need of any metal catalysts. The strain-promoted 1,3-dipolar cycloaddition of cyclooctynes and azides, also termed as the Cu-free click reaction, is a bioorthogonal reaction that enables the conjugation of two molecules in aqueous solution. DBCO PEG derivatives possess fast kinetics and stability in aqueous buffer. DBCO reagents can be used to label azide-modified biomolecules spontaneous without the need for toxic Cu catalysts. Meanwhile, maleimide group can react with sulfhydryl (Thoil) groups at pH 6.5-7.5 easily. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties:

  • White/off-white solid or viscous liquid depends on molecule weight;
  • Soluble in aqeous buffer and DMSO;

Copper-free Click reaction procedures:

  • Prepare the azide-containing reagents in reaction buffer.
  • Add DBCO reagents to azide containing reagents. Add 1 mol equivalent of limiting reagent to 1.5~3.0 mol equivalents of abundance reagent.
  • Incubate the reaction at room temperature for 2~4 hours or 2~12 hours at 4 0C.
  • Purify conjugates either by dialysis or size-exclusion chromatograph.

Storage Conditions:

  • Store at -20 0C. Desiccate. Protect from light. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

DBCO PEG Biotin, Biotin PEG DBCO Cat. No. PG2-BNDB-5k 5000 Da 20 mg修饰性聚乙二醇

发表于由
回复

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DBCO PEG Biotin, Biotin PEG DBCO

Cat. No. PG2-BNDB-5k
Specification 5000 Da
Unit Size 20 mg
Price $385.00

Qty Add to Cart

Description:

DBCO (dibenzocycolctyne) PEG Biotin derivatives can go Click Chemistry reaction without a need of any metal catalysts. The strain-promoted 1,3-dipolar cycloaddition of cyclooctynes and azides, also termed as the Cu-free click reaction, is a bioorthogonal reaction that enables the conjugation of two molecules in aqueous solution. DBCO PEG derivatives possess fast kinetics and stability in aqueous buffer. DBCO reagents can be used to label azide-modified biomolecules spontaneous without the need for toxic Cu catalysts. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties:

  • White solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Copper-free Click reaction procedures:

  • Prepare the azide-containing reagents in reaction buffer.
  • Add DBCO reagents to azide containing reagents. Add 1 mol equivalent of limiting reagent to 1.5~3.0 mol equivalents of abundance reagent.
  • Incubate the reaction at room temperature for 2~4 hours or 2~12 hours at 4 0C.
  • Purify conjugates either by dialysis or size-exclusion chromatograph.

Storage Conditions:

  • Store at -20 0C, dessicate. Protect from light. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

DBCO PEG Biotin, Biotin PEG DBCO Cat. No. PG2-BNDB-3k 3400 Da 20 mg修饰性聚乙二醇

发表于由
回复

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DBCO PEG Biotin, Biotin PEG DBCO

Cat. No. PG2-BNDB-3k
Specification 3400 Da
Unit Size 20 mg
Price $385.00

Qty Add to Cart

Description:

DBCO (dibenzocycolctyne) PEG Biotin derivatives can go Click Chemistry reaction without a need of any metal catalysts. The strain-promoted 1,3-dipolar cycloaddition of cyclooctynes and azides, also termed as the Cu-free click reaction, is a bioorthogonal reaction that enables the conjugation of two molecules in aqueous solution. DBCO PEG derivatives possess fast kinetics and stability in aqueous buffer. DBCO reagents can be used to label azide-modified biomolecules spontaneous without the need for toxic Cu catalysts. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties:

  • White solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Copper-free Click reaction procedures:

  • Prepare the azide-containing reagents in reaction buffer.
  • Add DBCO reagents to azide containing reagents. Add 1 mol equivalent of limiting reagent to 1.5~3.0 mol equivalents of abundance reagent.
  • Incubate the reaction at room temperature for 2~4 hours or 2~12 hours at 4 0C.
  • Purify conjugates either by dialysis or size-exclusion chromatograph.

Storage Conditions:

  • Store at -20 0C, dessicate. Protect from light. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

DBCO PEG Biotin, Biotin PEG DBCO Cat. No. PG2-BNDB-2k 2000 Da 20 mg修饰性聚乙二醇

发表于由
回复

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DBCO PEG Biotin, Biotin PEG DBCO

Cat. No. PG2-BNDB-2k
Specification 2000 Da
Unit Size 20 mg
Price $425.00

Qty Add to Cart

Description:

DBCO (dibenzocycolctyne) PEG Biotin derivatives can go Click Chemistry reaction without a need of any metal catalysts. The strain-promoted 1,3-dipolar cycloaddition of cyclooctynes and azides, also termed as the Cu-free click reaction, is a bioorthogonal reaction that enables the conjugation of two molecules in aqueous solution. DBCO PEG derivatives possess fast kinetics and stability in aqueous buffer. DBCO reagents can be used to label azide-modified biomolecules spontaneous without the need for toxic Cu catalysts. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties:

  • White solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Copper-free Click reaction procedures:

  • Prepare the azide-containing reagents in reaction buffer.
  • Add DBCO reagents to azide containing reagents. Add 1 mol equivalent of limiting reagent to 1.5~3.0 mol equivalents of abundance reagent.
  • Incubate the reaction at room temperature for 2~4 hours or 2~12 hours at 4 0C.
  • Purify conjugates either by dialysis or size-exclusion chromatograph.

Storage Conditions:

  • Store at -20 0C, dessicate. Protect from light. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

DBCO PEG DSPE, DSPE PEG DBCO Cat. No. PG2-DBDS-5k 5000 Da 20 mg修饰性聚乙二醇

发表于由
回复

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DBCO PEG DSPE, DSPE PEG DBCO

Cat. No. PG2-DBDS-5k
Specification 5000 Da
Unit Size 20 mg
Price $385.00

Qty Add to Cart

Synonym: 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine PEG DBCO, DSPE PEG5000 DBCO, DBCO PEG5000 DSPE

Description:

DSPE PEG DBCO (dibenzocyclooctyne) is one of Nanocs' reactive phospholipid PEG derivatives that can react with azide group via copper free Click Chemistry. DSPE (1,2-distearoyl-sn-glycero-3-phosphoethanolamine) is an 18 carbon saturated phospholipid that is covalently attached to the one terminus of PEG chain. DBCO, on the other hand, is linked to the other end of the PEG that can go Click Chemistry with azide without need any catalyst. Reaction between DBCO and azide allows the  conjugation of DSPE PEG to azido functionalized molecules or materials with high efficiency. The strain-promoted 1,3-dipolar cycloaddition of cyclooctynes and azides, also termed as the Cu-free click reaction, is a bioorthogonal reaction that enables the conjugation of two molecules in aqueous solution. DBCO PEG derivatives possess fast kinetics and stability in aqueous buffer. 

Product information:

  • Form: Solid;
  • Color: Pale yellow to yellow;
  • Solubility: Soluble in chloroform, warm water;
  • Reactive group: DBCO;
  • Reactive to: Azide (-N3);
  • Lipid type: C18 phospholipid, saturated;
  • Purity: >95%;

Copper-free Click reaction procedures:

  • Prepare the azide-containing reagents in reaction buffer.
  • Add DBCO reagents to azide containing reagents. Add 1 mol equivalent of limiting reagent to 1.5~3.0 mol equivalents of abundance reagent.
  • Incubate the reaction at room temperature for 2~4 hours or 2~12 hours at 4 0C.
  • Purify conjugates either by dialysis or size-exclusion chromatograph.

Storage Conditions:

  • Store at -20 0C. Protect from light. Avoid frequent thaw and freeze. 
Documents
  • SDS
  • DataSheet

Related Products
PG2-DSNS-5k , DSPE-PEG-NHS
PG2-DSML-5k , DSPE PEG Maleimide, DSPE-PEG-MAL
PG2-AMDS-5k , DSPE PEG Amine, DSPE-PEG-NH2
PG2-DMML-5k , DMPE PEG Maleimide, DMPE-PEG-Mal

DBCO PEG DSPE, DSPE PEG DBCO Cat. No. PG2-DBDS-3k 3400 Da 20 mg修饰性聚乙二醇

发表于由
回复

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DBCO PEG DSPE, DSPE PEG DBCO

Cat. No. PG2-DBDS-3k
Specification 3400 Da
Unit Size 20 mg
Price $385.00

Qty Add to Cart

Synonym: 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine PEG DBCO, DSPE PEG DBCO

Description:

DSPE PEG DBCO (dibenzocyclooctyne) is one of Nanocs' reactive phospholipid PEG derivatives that can react with azide group via copper free Click Chemistry. DSPE (1,2-distearoyl-sn-glycero-3-phosphoethanolamine) is an 18 carbon saturated phospholipid that is covalently attached to the one terminus of PEG chain. DBCO, on the other hand, is linked to the other end of the PEG that can go Click Chemistry with azide without need any catalyst. Reaction between DBCO and azide allows the  conjugation of DSPE PEG to azido functionalized molecules or materials with high efficiency. The strain-promoted 1,3-dipolar cycloaddition of cyclooctynes and azides, also termed as the Cu-free click reaction, is a bioorthogonal reaction that enables the conjugation of two molecules in aqueous solution. DBCO PEG derivatives possess fast kinetics and stability in aqueous buffer. 

Product information:

  • Form: Solid;
  • Color: Pale yellow to yellow;
  • Solubility: Soluble in chloroform, warm water;
  • Reactive group: DBCO;
  • Reactive to: Azide (-N3);
  • Lipid type: C18 phospholipid, saturated;
  • Purity: >95%;

Copper-free Click reaction procedures:

  • Prepare the azide-containing reagents in reaction buffer.
  • Add DBCO reagents to azide containing reagents. Add 1 mol equivalent of limiting reagent to 1.5~3.0 mol equivalents of abundance reagent.
  • Incubate the reaction at room temperature for 2~4 hours or 2~12 hours at 4 0C.
  • Purify conjugates either by dialysis or size-exclusion chromatograph.

Storage Conditions:

  • Store at -20 0C. Protect from light. Avoid frequent thaw and freeze. 
Documents
  • SDS
  • DataSheet

Related Products
PG2-DSNS-3k , DSPE-PEG-NHS
PG2-DSML-3k , DSPE PEG Maleimide, DSPE-PEG-MAL
PG2-AMDS-2k , DSPE PEG Amine, DSPE-PEG-NH2
PG2-AZDS-3k , DSPE PEG Azide, DSPE-PEG-N3

DBCO PEG Thiol, DBCO-PEG-SH Cat. No. PG2-DBTH-5k 5000 Da 20 mg修饰性聚乙二醇

发表于由

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DBCO PEG Thiol, DBCO-PEG-SH

Cat. No. PG2-DBTH-5k
Specification 5000 Da
Unit Size 20 mg
Price $385.00

Qty Add to Cart

Description:

DBCO (dibenzocycolctyne) PEG thiol (DBCO-PEG-SH) derivatives can go Click Chemistry reaction without a need of any metal catalysts. The strain-promoted 1,3-dipolar cycloaddition of cyclooctynes and azides, also termed as the Cu-free click reaction, is a bioorthogonal reaction that enables the conjugation of two molecules in aqueous solution. DBCO PEG derivatives possess fast kinetics and stability in aqueous buffer. DBCO reagents can be used to label azide-modified biomolecules spontaneous without the need for toxic Cu catalysts. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties:

  • White solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Copper-free Click reaction procedures:

  • Prepare the azide-containing reagents in reaction buffer.
  • Add DBCO reagents to azide containing reagents. Add 1 mol equivalent of limiting reagent to 1.5~3.0 mol equivalents of abundance reagent.
  • Incubate the reaction at room temperature for 2~4 hours or 2~12 hours at 4 0C.
  • Purify conjugates either by dialysis or size-exclusion chromatograph.

Storage Conditions:

  • Store at -20 0C, desiccate. Protect from light. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

DBCO PEG Silane Cat. No. PG2-DBSL-5k 5000 Da 20 mg修饰性聚乙二醇

发表于由

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DBCO PEG Silane

Cat. No. PG2-DBSL-5k
Specification 5000 Da
Unit Size 20 mg
Price $385.00

Qty Add to Cart

Description:

DBCO (dibenzocycolctyne) PEG Silane derivatives can go Click Chemistry reaction without a need of any metal catalysts. The strain-promoted 1,3-dipolar cycloaddition of cyclooctynes and azides, also termed as the Cu-free click reaction, is a bioorthogonal reaction that enables the conjugation of two molecules in aqueous solution. DBCO PEG derivatives possess fast kinetics and stability in aqueous buffer. DBCO reagents can be used to label azide-modified biomolecules spontaneous without the need for toxic Cu catalysts. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties:

  • White solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Copper-free Click reaction procedures:

  • Prepare the azide-containing reagents in reaction buffer.
  • Add DBCO reagents to azide containing reagents. Add 1 mol equivalent of limiting reagent to 1.5~3.0 mol equivalents of abundance reagent.
  • Incubate the reaction at room temperature for 2~4 hours or 2~12 hours at 4 0C.
  • Purify conjugates either by dialysis or size-exclusion chromatograph.

Storage Conditions:

  • Store at -20 0C, dessicate. Protect from light. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

DBCO PEG Cy5 Cat. No. PG2-DBS5-5k 5000 Da 5 mg修饰性聚乙二醇

发表于由

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DBCO PEG Cy5

Cat. No. PG2-DBS5-5k
Specification 5000 Da
Unit Size 5 mg
Price $385.00

Qty Add to Cart

Description:

DBCO (dibenzocycolctyne) PEG Cy5 is a near-infrared fluorescent PEG derivative that can go Click Chemistry reaction without a need of any metal catalysts. The strain-promoted 1,3-dipolar cycloaddition of cyclooctynes and azides, also termed as the Cu-free click reaction, is a bioorthogonal reaction that enables the conjugation of two molecules in aqueous solution. DBCO PEG derivatives possess fast kinetics and stability in aqueous buffer. DBCO reagents can be used to label azide-modified biomolecules spontaneous without the need for toxic Cu catalysts. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties:

  • Dark blue solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Copper-free Click reaction procedures:

  • Prepare the azide-containing reagents in reaction buffer.
  • Add DBCO reagents to azide containing reagents. Add 1 mol equivalent of limiting reagent to 1.5~3.0 mol equivalents of abundance reagent.
  • Incubate the reaction at room temperature for 2~4 hours or 2~12 hours at 4 0C.
  • Purify conjugates either by dialysis or size-exclusion chromatograph.

Storage Conditions:

  • Store at -20 0C, dessicate. Protect from light. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

DBCO PEG Cy3 Cat. No. PG2-DBS3-5k 5000 Da 5 mg修饰性聚乙二醇

发表于由

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DBCO PEG Cy3

Cat. No. PG2-DBS3-5k
Specification 5000 Da
Unit Size 5 mg
Price $385.00

Qty Add to Cart

Description:

DBCO (dibenzocycolctyne) PEG Cy3 is a red fluorescent PEG derivative that can go Click Chemistry reaction without a need of any metal catalysts. The strain-promoted 1,3-dipolar cycloaddition of cyclooctynes and azides, also termed as the Cu-free click reaction, is a bioorthogonal reaction that enables the conjugation of two molecules in aqueous solution. DBCO PEG derivatives possess fast kinetics and stability in aqueous buffer. DBCO reagents can be used to label azide-modified biomolecules spontaneous without the need for toxic Cu catalysts. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties:

  • Dark red solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Copper-free Click reaction procedures:

  • Prepare the azide-containing reagents in reaction buffer.
  • Add DBCO reagents to azide containing reagents. Add 1 mol equivalent of limiting reagent to 1.5~3.0 mol equivalents of abundance reagent.
  • Incubate the reaction at room temperature for 2~4 hours or 2~12 hours at 4 0C.
  • Purify conjugates either by dialysis or size-exclusion chromatograph.

Storage Conditions:

  • Store at -20 0C, dessicate. Protect from light. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet