BRD4 Inhibitor-17

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

BRD4 Inhibitor-17 

BRD4 Inhibitor-17 (Compound 5i) 是一种有效的 BRD4 抑制剂，IC50 为 0.33 μM。BRD4 Inhibitor-17 在调节炎症、增殖和细胞周期基因的转录中起关键作用。BRD4 Inhibitor-17 可作为砷类药物的潜在解毒剂。

BRD4 Inhibitor-17

BRD4 Inhibitor-17 Chemical Structure

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生物活性

BRD4 Inhibitor-17 (Compound 5i) is a potent inhibitor of BRD4 with an IC50 of 0.33 μM. BRD4 Inhibitor-17 plays crucial role in regulating transcription of inflammatory, proliferation and cell cycle genes. BRD4 Inhibitor-17 serves as potential antidotes for arsenicals[1].

分子量

349.38

Formula

C16H16FN3O3S
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Yatchang MF, et al. Development of BRD4 inhibitors as anti-inflammatory agents and antidotes for arsenicals. Bioorg Med Chem Lett. 2022;64:128696.

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