Cereblon inhibitor 1

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Cereblon inhibitor 1 

Cereblon inhibitor 1 是一种异吲哚啉衍生物,一种 cereblon E3 泛素连接酶调节药物。 Cereblon inhibitor 1 具有用于癌症研究的潜力。

Cereblon inhibitor 1

Cereblon inhibitor 1 Chemical Structure

CAS No. : 2672489-14-2

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生物活性

Cereblon inhibitor 1, an isoindoline derivative, is a cereblon E3 ubiquitin ligase modulating drug. Cereblon inhibitor 1 has the potential for cancer research[1].

IC50 & Target[1]

Cereblon

 

体外研究
(In Vitro)

Cereblon inhibitor 1 (compound CM-48) suppresses MM.1S cell proliferation (IC50=0.0365 nM)[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

620.05

Formula

C32H28ClF2N5O4

CAS 号

2672489-14-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Hui Liu, et al. Isoindoline derivative and its application. WO2021147889A1.

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