ATR-IN-10

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

ATR-IN-10 

ATR-IN-10 是一种有效且高选择性 ATR 激酶的抑制剂，其IC50值为 2.978 μM。

ATR-IN-10

ATR-IN-10 Chemical Structure

CAS No. : 2713577-93-4

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生物活性

ATR-IN-10 is a potent and highly selective inhibitor of ataxia telangiectasia mutated and Rad3-Related (ATR) kinase with an IC50 value of 2.978 μM.

IC50 & Target

ATR

2.978 μM (IC50)

分子量

420.51

Formula

C27H24N4O
CAS 号

2713577-93-4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Bin H, et al. Discovery of a potent and highly selective inhibitor of ataxia telangiectasia mutated and Rad3-Related (ATR) kinase: Structural activity relationship and antitumor activity both in vitro and in vivo. Eur J Med Chem. 2022 Feb 12;232:114187.

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