Porfiromycin(Synonyms: N-Methylmitomycin C; NSC-56410; U-14743)

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Porfiromycin (Synonyms: N-Methylmitomycin C; NSC-56410; U-14743)

孔磺霉素是一种生物还原性烷化剂,相对于其他需氧的烷化剂,它能优先杀死缺氧的肿瘤细胞。

Porfiromycin(Synonyms: N-Methylmitomycin C;  NSC-56410;  U-14743)

Porfiromycin Chemical Structure

CAS No. : 801-52-5

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生物活性

Porfiromycin is a bioreductive alkylating agent that preferentially kill hypoxic tumor cells relative to other aerobic counterparts.

分子量

348.35

Formula

C16H20N4O5

CAS 号

801-52-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Keyes SR, Rockwell S, Sartorelli AC. Porfiromycin as a bioreductive alkylating agent with selective toxicity to hypoxic EMT6 tumor cells in vivo and in vitro. Cancer Res. 1985;45(8):3642-3645.

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