UCM 608(Synonyms: 2-Phenylmelatonin)

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UCM 608 (Synonyms: 2-Phenylmelatonin)

UCM 608 是一种高亲和力的褪黑素 (MT) 膜受体激动剂。MT1MT2pKi 值分别为 10.7 和 10.4。

UCM 608(Synonyms: 2-Phenylmelatonin)

UCM 608 Chemical Structure

CAS No. : 151889-03-1

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生物活性

UCM 608 is a high affinity melatonin (MT) membrane receptor agonist. The pKi values for MT1 and MT2 are 10.7 and 10.4[1][2].

IC50 & Target

pKi: 10.7 (MT1)[1].
pKi: 10.4 (MT2)[1]

体外研究
(In Vitro)

UCM 608 is a high affinity melatonin membrane receptor agonist. The pKi values for MT1 and MT2 are 10.7 and 10.4 [1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

308.37

Formula

C19H20N2O2

CAS 号

151889-03-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Radogna F, et al. Rapid and transient stimulation of intracellular reactive oxygen species by melatonin in normal and tumor leukocytes. Toxicol Appl Pharmacol. 2009;239(1):37-45.

    [2]. Mor, M., et al. Synthesis, pharmacological characterization and QSAR studies on 2-substituted indole melatonin receptor ligands. Bioorganic & Medicinal Chemistry, 9(4), 1045–1057.

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