Lycorenine(Synonyms: 石蒜裂碱)

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Lycorenine (Synonyms: 石蒜裂碱)

Lycorenine 是一种具有血管减压作用的生物碱。Lycorenine 还显示出抗癌和抗菌活性。

Lycorenine(Synonyms: 石蒜裂碱)

Lycorenine Chemical Structure

CAS No. : 477-19-0

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生物活性

Lycorenine is an alkaloid that has vasodepressor action. Lycorenine also exhibits anticancer and antibacterial activities[1][2][3].

体外研究
(In Vitro)

Lycorenine inhibits the cell viability, with IC50s of 0.8 and 1.2 μg/mL for LMTK and HEPG2 cells, respectively[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究
(In Vivo)

Lycorenine (1-10 mg/kg i.v.) produces dose-related decreases in blood pressure and heart rate in anesthetized rats[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

317.38

Formula

C18H23NO4
CAS 号

477-19-0
中文名称

石蒜裂碱
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Miyasaka K, et, al. Pharmacological studies of lycorenine, an alkaloid of Lycoris radiata Herb.: Vasodepressor mechanism in rats. Jpn J Pharmacol. 1979 Aug;29(4):605-22.

    [2]. Weniger B, et, al. Cytotoxic activity of Amaryllidaceae alkaloids. Planta Med. 1995 Feb;61(1):77-9.

    [3]. Gu D, et, al. Antibacterial Phytosterols and Alkaloids from Lycoris radiate. Natural Product Sciences. 2014 Jou; 20(2): 107-112.

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