Mal-PEG8-Val-Cit-PAB-MMAE

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Mal-PEG8-Val-Cit-PAB-MMAE 

Mal-PEG8-Val-Cit-PAB-MMAE 是抗体偶联药物 ADC 的一部分 (drug-linker conjugate for ADC)。Mal-PEG8-Val-Cit-PAB-MMAE 包含一个可降解的 ADC linker 和一个有效的微管蛋白抑制剂 MMAE (HY-15162)。

Mal-PEG8-Val-Cit-PAB-MMAE

Mal-PEG8-Val-Cit-PAB-MMAE Chemical Structure

CAS No. : 2353409-69-3

规格 是否有货
25 mg 询价
50 mg 询价

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生物活性

Mal-PEG8-Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC. Mal-PEG8-Val-Cit-PAB-MMAE contains a cleavable ADC linker and a potent tubulin inhibitor MMAE (HY-15162)[1].

IC50 & Target

Auristatin

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

1626.97

Formula

C81H131N11O23

CAS 号

2353409-69-3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

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