m-PEG5-2-methylacrylate

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m-PEG5-2-methylacrylate 

m-PEG5-2-methylacrylate 是一种 PROTAC linker,属于 PEG 和 Alkyl/ester 类,可用于合成 PROTAC。

m-PEG5-2-methylacrylate

m-PEG5-2-methylacrylate Chemical Structure

CAS No. : 48074-75-5

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生物活性

m-PEG5-2-methylacrylate is a PEG- and Alkyl/ester-based PROTAC linker can be used in the synthesis of PROTACs[1].

IC50 & Target[1]

PEGs

 

Alkyl/ether

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

320.38

Formula

C15H28O7

CAS 号

48074-75-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Yong Ku Kwon,et al. Reduced excimer formation in polyfluorenes by introducing coil-like poly[penta(ethylene glycol) methyl ether methacrylate] block segments. Macromolecules, 2009, 42(3), 887-891.

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