Acid-PEG4-C2-Boc

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Acid-PEG4-C2-Boc 

Acid-PEG4-C2-Boc 是一种 PROTAC linker,属于 PEGAlkyl/ether 类,可以用于合成抑制 mTOR 的 PROTAC。

Acid-PEG4-C2-Boc

Acid-PEG4-C2-Boc Chemical Structure

CAS No. : 1835759-85-7

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

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生物活性

Acid-PEG4-C2-Boc is a PEG– and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs for the inhibition of mTOR[1].

IC50 & Target

PEGs

 

Alkyl/ether

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

350.40

Formula

C16H30O8

CAS 号

1835759-85-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献
  • [1]. Jennifer PITZEN , et al. C40-, c28-, and c-32-linked rapamycin analogs as mtor inhibitors. WO2019212990A1.

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