Biotin-bis-amido-SS-NHS

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Biotin-bis-amido-SS-NHS 

Biotin-bis-amido-SS-NHS 是一种基于 Alkyl/ether 结构的 PROTAC linker,可用于 PROTAC 的合成。

Biotin-bis-amido-SS-NHS

Biotin-bis-amido-SS-NHS Chemical Structure

CAS No. : 142439-92-7

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生物活性

Biotin-bis-amido-SS-NHS is an Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.

IC50 & Target[1]

Alkyl/ether

 

体外研究
(In Vitro)

Biotin-bis-amido-SS-NHS is a long arm biotin containing disulfide bond, and the compound can be applied to biochemistry detection field, reduce the influence of steric effect, improve the sensitivity of detection[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

575.72

Formula

C22H33N5O7S3

CAS 号

142439-92-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Liyanping, et al. A kind of long arm biotin containing disulfide bond and preparation method thereof. Patent CN107383054A.

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