Mal-PEG2-Val-Cit-amido-PAB-OH

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Mal-PEG2-Val-Cit-amido-PAB-OH 

Mal-PEG2-Val-Cit-amido-PAB-OH 是一种可降解 (cleavable) 的 ADC linker,用于抗体偶联药物 (ADCs) 的合成。 Mal-PEG2-Val-Cit-amido-PAB-OH 也可用作 PROTAC 的 Linker,可用于 PROTAC 的合成。

Mal-PEG2-Val-Cit-amido-PAB-OH

Mal-PEG2-Val-Cit-amido-PAB-OH Chemical Structure

CAS No. : 2055041-38-6

规格 是否有货
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生物活性

Mal-PEG2-Val-Cit-amido-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-Val-Cit-amido-PAB-OH also can be used as a PROTAC linker that can be used in the synthesis of PROTACs.

IC50 & Target

Cleavable

 

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

618.68

Formula

C29H42N6O9

CAS 号

2055041-38-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

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