Bis-propargyl-PEG4

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Bis-propargyl-PEG4  纯度: 95.64%

Bis-propargyl-PEG4 是一种用于合成 PORTAC 的 PROTAC linker,属于 PEG 类。Bis-propargyl-PEG2 被用于合成去甲万古霉素。

Bis-propargyl-PEG4

Bis-propargyl-PEG4 Chemical Structure

CAS No. : 159428-42-9

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生物活性

Bis-propargyl-PEG4 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG4 is used for the synthesis of demethylvancomycin dimers[1][2].

体外研究
(In Vitro)

Bis-propargyl-PEG4 can be used in the synthesis of demethylvancomycin dimers against vancomycin-resistant enterococcus faecalis[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

270.32

Formula

C14H22O5

CAS 号

159428-42-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献
  • [1]. Pearlie BURNETTE, et al. Dimeric immuno-modulatory compounds against cereblon-based mechanisms. WO2020014489A2.

    [2]. Jiang, et al. Design, synthesis and biological activity of novel demethylvancomycin dimers against vancomycin-resistant enterococcus faecalis. Tetrahedron, 2018: 74(27), 3527–3533.

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