m-PEG3-CH2COOH

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m-PEG3-CH2COOH 

m-PEG3-CH2COOH 是一种基于 PEG 的 PROTAC linker,用于 PROTAC 合成。

m-PEG3-CH2COOH

m-PEG3-CH2COOH Chemical Structure

CAS No. : 16024-60-5

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生物活性

m-PEG3-CH2COOH is a PEG-based based PROTAC linker can be used in the synthesis of PROTACs.

IC50 & Target[1]

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

222.24

Formula

C9H18O6

CAS 号

16024-60-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献
  • [1]. Chen X, et al. Histidine-Specific Peptide Modification via Visible-Light-Promoted C-H Alkylation. J Am Chem Soc. 2019 Nov 13;141(45):18230-18237.

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