PEG3-O-CH2COOH(Synonyms: PROTAC Linker 8)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

PEG3-O-CH2COOH (Synonyms: PROTAC Linker 8)

PEG3-O-CH2COOH (PROTAC Linker 8) 是一种 PROTAC linker，属于 PEG 类。PEG3-O-CH2COOH 可用于合成 SNIPER 分子。

PEG3-O-CH2COOH(Synonyms: PROTAC Linker 8)

PEG3-O-CH2COOH Chemical Structure

CAS No. : 51951-05-4

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生物活性

PEG3-O-CH2COOH (PROTAC Linker 8) is a PEG-based PROTAC linker can be used in the synthesis of SNIPERs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PEG3-O-CH2COOH (Compound 15b) is a PROTAC linker can be used in the synthesis of a series of SNIPER(ER)s. SNIPERs that recruit inhibitor of the apoptosis protein (IAP) ubiquitin ligases to specifically degrade targeted proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

208.21

Formula

C8H16O6
CAS 号

51951-05-4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Ohoka N, et al. In Vivo Knockdown of Pathogenic Proteins via Specific and Nongenetic Inhibitor of Apoptosis Protein (IAP)-dependent Protein Erasers (SNIPERs). J Biol Chem. 2017 Mar 17;292(11):4556-4570.

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