LSD1/HDAC6-IN-1

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

LSD1/HDAC6-IN-1 

LSD1/HDAC6-IN-1 是一种具有口服活性的组蛋白去甲基化酶 LSD1 和组蛋白去乙酰酶 HDAC6 (LSD1/HDAC6) 双重抑制剂,具有抗肿瘤活性。LSD1/HDAC6-IN-1 可用于多发性骨髓瘤 (MM) 的研究。

LSD1/HDAC6-IN-1

LSD1/HDAC6-IN-1 Chemical Structure

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5 mg ¥3900 询问价格 & 货期
10 mg ¥6250 询问价格 & 货期
25 mg ¥12500 询问价格 & 货期

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生物活性

LSD1/HDAC6-IN-1 is an orally active dual inhibitor of lysine specific demethylase 1(LSD1)/Histone deacetylase 6 (HDAC6), with anti-tumor activity. LSD1/HDAC6-IN-1 can be used for the research of multiple myeloma (MM)[1].

体外研究
(In Vitro)

LSD1/HDAC6-IN-1 shows superior potency in multiple MM lines[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

LSD1/HDAC6-IN-1 is efficacy in the MM.1S xenograft model[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

407.55

Formula

C50H66N6O4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. M Naveen Sadhu, et al. Novel dual LSD1/HDAC6 inhibitors for the treatment of multiple myeloma. Bioorg Med Chem Lett. 2020 Dec 24;34:127763.

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