TDP1 Inhibitor-1

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

TDP1 Inhibitor-1 

TDP1 Inhibitor-1 是一种酪酰 DNA 磷酸二酯酶 1 (TDP1) 有效抑制剂，IC50 值为 7 μM。

TDP1 Inhibitor-1

TDP1 Inhibitor-1 Chemical Structure

CAS No. : 2248702-80-7

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生物活性

TDP1 Inhibitor-1 is a potent Tyrosyl-DNA Phosphodiesterase 1 (TDP1) inhibitor with an IC50 of 7 μM[1].

IC50 & Target

IC50: 7 μM (Tyrosyl-DNA Phosphodiesterase 1)[1]
分子量

446.50

Formula

C26H26N2O5
CAS 号

2248702-80-7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Zhang XR, et al. Discovery, Synthesis, and Evaluation of Oxynitidine Derivatives as Dual Inhibitors of DNA Topoisomerase IB (TOP1) and Tyrosyl-DNA Phosphodiesterase 1 (TDP1), and Potential Antitumor Agents. J Med Chem. 2018 Nov 21;61(22):9908-9930.

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