NH2-PEG1-CH2CH2-Boc

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NH2-PEG1-CH2CH2-Boc 

NH2-PEG1-CH2CH2-Boc 是一种PROTAC linker,属于 PEGAlkyl/ether 类,可以用于合成PROTAC。

NH2-PEG1-CH2CH2-Boc

NH2-PEG1-CH2CH2-Boc Chemical Structure

CAS No. : 1260092-46-3

规格 价格 是否有货 数量
100 mg ¥1500 In-stock
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生物活性

NH2-PEG1-CH2CH2-Boc is a PEG– and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

Alkyl/ether

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

189.25

Formula

C9H19NO3

CAS 号

1260092-46-3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

参考文献
  • [1]. Qiu X, et al. Chemoselective Synthesis of Lenalidomide-Based PROTAC Library Using Alkylation Reaction. Org Lett. 2019 May 17;21(10):3838-3841.

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