hCAII-IN-1

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

hCAII-IN-1 

hCAII-IN-1 (compound 7f) 是一种有效的、选择性的碳酸酐酶 (CA II/IX) 抑制剂，Kis 分别为 1.2 和 113.6 nM。hCAII-IN-1 具有研究癌症疾病的潜力。

hCAII-IN-1

hCAII-IN-1 Chemical Structure

CAS No. : 1807520-24-6

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生物活性

hCAII-IN-1 (compound 7f) is a potent and selective inhibitor of carbonic anhydrase (CA II/IX) with Kis of 1.2 and 113.6 nM, respectively. hCAII-IN-1 has the potential for the research of cancer diseases[1].

分子量

533.40

Formula

C21H21BrN6O4S
CAS 号

1807520-24-6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Nocentini A, et al. Sulfonamide/sulfamate switch with a series of piperazinylureido derivatives: Synthesis, kinetic and in silico evaluation as carbonic anhydrase isoforms I, II, IV, and IX inhibitors. Eur J Med Chem. 2020;186:111896.

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