ATM Inhibitor-2

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

ATM Inhibitor-2 

ATM Inhibitor -2 (化合物 7) 是一种强效的选择性 ATM 抑制剂,其 IC50 为 <1 nM。

ATM Inhibitor-2

ATM Inhibitor-2 Chemical Structure

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生物活性

ATM Inhibitor-2 (compound 7) is a potent and selective ATM inhibitor, with an IC50 of <1 nm[1].

IC50 & Target

ATM

<1 nM (IC50)

分子量

489.57

Formula

C26H31N7O3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Dimitrov T, et al. Development of novel urea-based ATM kinase inhibitors with subnanomolar cellular potency and high kinome selectivity. Eur J Med Chem. 2022 May 5;235:114234.

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