Cdc7-IN-18

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Cdc7-IN-18 

Cdc7-IN-18 (compound 1-2) 是一种有效的 CDC7 抑制剂，对 Cdc7/DBF4 酶的 IC50 为 1.29 nM。Cdc7-IN-18 在 COLO205 细胞中显示出抗增殖活性，IC50 为 53.62 nM。

Cdc7-IN-18

Cdc7-IN-18 Chemical Structure

CAS No. : 2562329-14-8

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生物活性

Cdc7-IN-18 (compound 1-2) is a potent CDC7 inhibitor with an IC50 of 1.29 nM for Cdc7/DBF4 enzyme. Cdc7-IN-18 shows antiproliferative activities with IC50 of 53.62 nM in COLO205 cells[1].

IC50 & Target[1]

Cdc7

1.29 nM (IC50)

分子量

367.47

Formula

C19H21N5OS
CAS 号

2562329-14-8
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Li Gang, et al. Tetracyclic compounds as cdc7 inhibitors. WO2020239107A1.

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