Microtubule inhibitor 7

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Microtubule inhibitor 7 

化合物17o（IC50= 14.0 nM，NCI-H460）和17p（IC50= 2.9 nM，NCI-H460）与呋喃基团在纳摩尔水平上对各种人类癌细胞系表现出有效的细胞毒性活性。

Microtubule inhibitor 7

Microtubule inhibitor 7 Chemical Structure

CAS No. : 2416338-65-1

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生物活性

Compounds 17O (ic50= 14.0 nm, NCI-H460) and 17p (ic50= 2.9 nm, NCI-H460) and furan groups showed effective cytotoxic activity against various human cancer cell lines at the nanomolar level.

分子量

446.43

Formula

C25H19FN2O5
CAS 号

2416338-65-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Ding Z,et al. Structure-based design and synthesis of novel furan-diketopiperazine-type derivatives as potent microtubule inhibitors for treating cancer. Bioorg Med Chem. 2020 May 15;28(10):115435.

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