CMD178 TFA

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CMD178 TFA  纯度: 98.72%

CMD178 TFA 是一种先导肽，能够持续地通过抑制 IL-2/s IL-2Rα 信号通路来减少 Foxp3 和 STAT5 的表达，并可抑制 Treg 细胞的发育。

CMD178 TFA

CMD178 TFA Chemical Structure

规格 价格 是否有货 数量
1 mg ￥3500 In-stock
5 mg ￥6500 In-stock
10 mg ￥10500 In-stock
50 mg   询价  
100 mg   询价  

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CMD178 TFA 相关产品

•相关化合物库:

  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

CMD178 TFA is a lead peptide that consistently reduced the expression of Foxp3 and STAT5 induced by IL-2/s IL-2Rα signaling and inhibits Treg cell development[1].

体外研究
(In Vitro)

CMD178 TFA (100 mM) suppresses IL-2-induced STAT5 phosphorylation and inhibits Foxp3 expression in T cells[1].
CMD178 TFA (100 mM) inhibits the development of Treg cells induced by IL2/sIL-2Rα signaling[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

964.05

Formula

C9H8F5KO3Y
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
参考文献

  • [1]. Price-Troska T, et, al. Inhibiting IL-2 signaling and the regulatory T-cell pathway using computationally designed peptides. Invest New Drugs. 2019 Feb;37(1):9-16.

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