Bis-aminooxy-PEG1

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Bis-aminooxy-PEG1  纯度: ≥95.0%

Bis-aminooxy-PEG1 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

Bis-aminooxy-PEG1

Bis-aminooxy-PEG1 Chemical Structure

CAS No. : 93460-33-4

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100 mg ¥4500 In-stock
250 mg ¥7500 In-stock
500 mg ¥11000 In-stock
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生物活性

Bis-aminooxy-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

136.15

Formula

C4H12N2O3

CAS 号

93460-33-4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

参考文献
  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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