Bis-PEG6-acid

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Bis-PEG6-acid 

Bis-PEG6-acid 是一种 PROTAC linker,属于 PEG 类。Bis-PEG5-propionic acid 可用于合成一系列 PROTAC 分子。

Bis-PEG6-acid

Bis-PEG6-acid Chemical Structure

CAS No. : 119189-70-7

规格 价格 是否有货 数量
250 mg ¥1700 In-stock
500 mg ¥2800 In-stock
1 g   询价  
5 g   询价  

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生物活性

Bis-PEG6-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

IC50 & Target[1]

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

382.40

Formula

C16H30O10

CAS 号

119189-70-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献
  • [1]. Zorba A, et al. Delineating the role of cooperativity in the design of potent PROTACs for BTK. Proc Natl Acad Sci U S A. 2018 Jul 31;115(31):E7285-E7292.

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