环孢菌素C
基本信息
产品名称 | 环孢菌素C |
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英文名称 | Cyclosporin C |
英文别名 | Thr2-cyclosporin A; 7-L-Threonine-cyclosporin A; Thr2-cyclosporine; Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-3-hydroxy-N,4-dimethyl-L-2-amino-6-octenoyl-L-threonyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leu |
规格或纯度 | ≥95% |
运输条件 | 冰袋运输 |
一般描述
环孢菌素C是高度亲脂性的环肽天然产物,是环孢菌素系列抗真菌和免疫抑制剂化合物-环孢菌素A和B的成员。环孢菌素结合亲环蛋白细胞内蛋白,高度保守的蛋白参与肽基-脯氨酰键的顺反异构化和蛋白折叠。
Cyclosporin C is a highly lipophilic cyclic peptide natural product, a member of the cyclosporin series of antifungal and immunosuppresive compounds – Cyclosporin A and B . The cyclosporins bind the cyclophilin intracellular proteins, highly conserved proteins involved in|cis-trans|isomerization of peptidyl-prolyl bonds and protein folding.
相关属性
CAS编号 | 59787-61-0 |
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溶解性 | Soluble in 100% ethanol, acetone or ethyl acetate; insoluble in water. |
储存温度 | 2-8°C储存 |
分子量 | 1117.84 |
分子式 | C62H111N11O13 |
品牌 | Jinpan |
Smiles | C\\C=C\\C[C@@H](C)[C@@H](O)[C@@H]1N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@ |
PubChem CID | 6438160 |