Pentafluorophenyl PEG, mPEG-PFP Cat. No. PG1-PFP-10k 10000 Da 100 mg修饰性聚乙二醇

发表于2023年9月19日由上海金畔生物科技有限公司

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Pentafluorophenyl PEG, mPEG-PFP

Cat. No.	PG1-PFP-10k
Specification	10000 Da
Unit Size	100 mg
Price	$385.00

Description:

Nanocs PFP (pentafluorophenyl) functionalized polyethylene glycol (PEG-PFP) is an amine (-NH₂) reactive PEG derivative that can be used to modify molecules with available amine groups. Compared to NHS PEG, PFP PEG has greater reactivity, it can react with both prirmary and secondary amine groups at pH 7~9. Nanocs provides a number of PFP functionalized PEG derivatives that can be used for controlled amine pegylation applications.

Physical Properties:

Off-white/white solid or viscous liquid depends on molecule weight;
Solubility: 10 mg/mL, clear in water, chloroform, DMSO.
Purity: >95%

Storage Conditions:

Store at -20 ⁰C, desiccate. PFP PEG tends to hydrolyze from moisture. Avoid frequent thaw and freeze.

Documents

SDS
DataSheet

DSPE PEG Maleimide, DSPE-PEG-MAL Cat. No. PG2-DSML-10k 10000 Da 100 mg修饰性聚乙二醇

发表于2023年9月18日由上海金畔生物科技有限公司

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DSPE PEG Maleimide, DSPE-PEG-MAL

Cat. No.	PG2-DSML-10k
Specification	10000 Da
Unit Size	100 mg
Price	$385.00

Synonym: Maleimide PEG DSPE, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine PEG Maleimide, DSPE-PEG-Mal.

Description:

DSPE PEG Maleimide is one of Nanocs reactive phospholipid PEG reagents that can react with sulfhydryl (thiol, -SH) groups. DSPE (1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine) is a saturated 18C phospholipid that is highly hydrophobic. PEG linker (polyethylene glycol), on the other hand, offers good hydrophilicity and water solubility. Maleimide functional DSPE PEG has excellent reactivity towards sulfhydryl/thiol groups derived from various molecules. Reaction between maleimide and thiolproceeds easily at neutral pH. Maleimide PEG DSPE is one of most commonly used reactive phospholipids to conjugate antibodies, peptides or other ligands to the surface of liposome and other lipid PEG nanoparticles. Pegylated phospholipids have longer blood circulation time and higher stability for encapsulated drugs. Nanocs has developed a comprehensive collection of thiol reactive maleimide phospholipid PEG products that have high purity, various molecular weights and excellent chemical reactivity. These lipid PEG conjugates demonstrate excellent amphilphilic properties and offer superior advantages for small and large molecule drug formulation and delivery.

Physical Properties:

Form: Solid powder;
Color: White;
Solubility: Soluble in chloroform and warm water;
Reactive group: Maleimide;
Reactive to: Sulfhydryl (-SH);
Lipid type: 18C PE, saturated;
Purity: >95%

Storage Conditions:

Store at -20 ⁰C. Avoid frequent thaw and freeze.

Documents

SDS
DataSheet

Methacrylate PEG, mPEG-MAR Cat. No. PG1-MAR-350 350 Da 1 g修饰性聚乙二醇

发表于2023年9月18日由上海金畔生物科技有限公司

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Methacrylate PEG, mPEG-MAR

Cat. No.	PG1-MAR-350
Specification	350 Da
Unit Size	1 g
Price	$385.00

Description:

Methacrylate functionalized polyethylene glycol (PEG methacrylate) is a reactive PEG derivative that can be used to modify proteins, peptides and other materials via available acrylic groups. It is also a polymerizable PEG that can form biocompatible hydrogel. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties:

Off-white/white solid or viscous liquid depends on molecule weight;
Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

Store at -20 ⁰C, dessiccated Protect from light. Avoid frequent thaw and freeze.

Documents

SDS
DataSheet

Polystyrene beads, streptavidin coated Cat. No. PS1u-SV-2 1 um 1 mL修饰性聚乙二醇

发表于2023年9月18日由上海金畔生物科技有限公司

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Polystyrene beads, streptavidin coated

Cat. No.	PS1u-SV-2
Specification	1 um
Unit Size	1 mL
Price	$485.00

Description:

Polystyrene Particles from Nanocs have narrow size distribution yet with multiple size selection from 20 nm to 10 microns. These particles are suspended in 1% aqeuous solution. Standard deviation of these particles is in the range of 10% of listed size parameter. These particles have wide applications in diagnostic reagents and bioassay development. They can be further modified with different surface coatings and functional groups. Nanocs surface modified polystyrene particles provide more choices for in-vitro or in-vivo applications of those nanoparticles. Customer conjugation and modification is available upon request.

Physical Properties:

1% suspension in aqueous solution, other concentration available upon request;

Storage Conditions:

Store at 4 ⁰C.

Azido succinimidyl acetic acid NHS Cat. No. AZ2NS-02 100 mg修饰性聚乙二醇

发表于2023年9月18日由上海金畔生物科技有限公司

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Azido succinimidyl acetic acid NHS

Cat. No.	AZ2NS-02
Specification
Unit Size	100 mg
Price	$385.00

Surfactant free polystyrene beads Cat. No. PS900-SF-2 900 nm 5 mL修饰性聚乙二醇

发表于2023年9月18日由上海金畔生物科技有限公司

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Surfactant free polystyrene beads

Cat. No.	PS900-SF-2
Specification	900 nm
Unit Size	5 mL
Price	$485.00

Magnetic Nanoparticles, Concanavilin A Labeled Cat. No. MP25-CON-0.5 25~30 nm 0.5 mL修饰性聚乙二醇

发表于2023年9月18日由上海金畔生物科技有限公司

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Magnetic Nanoparticles, Concanavilin A Labeled

Cat. No.	MP25-CON-0.5
Specification	25~30 nm
Unit Size	0.5 mL
Price	$385.00

Description:

Nanocs provides various functionalized superparamagnetic particles that can be used for biomolecule separation, imaging and diagnostic application. Our small sized paramagnetic nanoparticles, with diameter in 25~50 nm, are suitable for fluorescent imaging, cellular and biomolecular labeling and magnetic sensing. Because of their small size, this type of magnetic nanoparticles cannot extracted with regular magnets. Our large size magnetic particles, with diameter 250 nm or above, can be exacted with magnets and therefore, can be used for cellular and biomolecule separation. Customer conjugation and modification is available upon request.

Physical Properties:

1% suspension in aqueous solution, other concentration available upon request;

Brownish or dark brown solution;

Storage Conditions:

Store at 4 ⁰C. Do not freeze.

Methoxy PEG Aldehyde, mPEG-CH2CHO Cat. No. PG1-AL-5k-1 5000 Da 1 g修饰性聚乙二醇

发表于2023年9月18日由上海金畔生物科技有限公司

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Methoxy PEG Aldehyde, mPEG-CH2CHO

Cat. No.	PG1-AL-5k-1
Specification	5000 Da
Unit Size	1 g
Price	$385.00

PEG Aldehyde Description:

Aldeyde PEG is an amine reactive PEG derivative that can be used to modify biomolecules via available amine groups. The reaction between aldehyde group with ε-amine of lysine residues and the α-amine at the N-terminus produces an intermediate Schiff base. Further reduction with hydride will form a stable C-N bond. PEG aldehydes react with amine groups at a pH of from 5.5 to 9.5. Higher pH will result in multiple Pegylation with both terminal and lysine groups. Aldehyde PEG is a commonly used PEG reagent for n-terminus pegylation in proteins or peptides.

Physical Properties:

Off-white/white solid or viscous liquid depends on molecule weight;
Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

Store at -20 ⁰C

Reaction Procedures:

Generally, a 10- to 50-fold molar excess of PEG aldehyde over the amount of amine-containing material results in sufficient conjugation.

Materials Required:

Pegylation buffer: Amine-free aqueous buffer, pH 6~8.5.
PEG aldehyde stock solution: 100 mg in 1 mL conjugation buffer.
Washing solution: Distilled water or any aqueous buffer.

Reaction Steps:

Dissolve targeted materials in pegylation buffer. Estimate the concentration of primary amine groups on the targeted materials. Add PEG aldehyde stock solution to the targeted conjugation materials with the final concentration keep at least 10 mg/mL. Allow mixture agitates at room temperature for 2~4 hrs at room temperature or overnight 4 ⁰C. After reaction, C=N bond can be reduced by sodium borohydride. Conjugate can be purified either by size exclusion chromatography or dialysis.

Documents

SDS
DataSheet

Pentafluorophenyl PEG, mPEG-PFP Cat. No. PG1-PFP-20k 20000 Da 100 mg修饰性聚乙二醇

发表于2023年9月18日由上海金畔生物科技有限公司

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Pentafluorophenyl PEG, mPEG-PFP

Cat. No.	PG1-PFP-20k
Specification	20000 Da
Unit Size	100 mg
Price	$385.00

Description:

Physical Properties:

Off-white/white solid or viscous liquid depends on molecule weight;
Solubility: 10 mg/mL, clear in water, chloroform, DMSO.
Purity: >95%

Storage Conditions:

Store at -20 ⁰C, desiccate. PFP PEG tends to hydrolyze from moisture. Avoid frequent thaw and freeze.

Documents

SDS
DataSheet

Lipoic acid PEG, mPEG-LA Cat. No. PG1-LA-5k 5000 Da 100 mg修饰性聚乙二醇

发表于2023年9月18日由上海金畔生物科技有限公司

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Lipoic acid PEG, mPEG-LA

Cat. No.	PG1-LA-5k
Specification	5000 Da
Unit Size	100 mg
Price	$325.00

Description:

Lipoic acid, also known as thioctic acid, is an important bioactive molecule participating in various biological processes. PEG functionalized lipoic acid can be used to bind to metallic particle or film surface with its -S-S-bond. Lipoic acid group has high affinity to metallic surfaces and have been widely used for gold nanoparticles and quantum dots surfaces. PEGylated lipoic acid is water soluble and can be used directly in aqueous buffer.

Physical Properties:

Off-yellow solid or viscous liquid depends on molecule weight;
Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

Store at -20 ⁰C, dessiccated Protect from light. Avoid frequent thaw and freeze.

Documents

SDS
DataSheet

Methacrylate PEG, mPEG-MAR Cat. No. PG1-MAR-350-5g 350 Da 5 g修饰性聚乙二醇

发表于2023年9月18日由上海金畔生物科技有限公司

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Methacrylate PEG, mPEG-MAR

Cat. No.	PG1-MAR-350-5g
Specification	350 Da
Unit Size	5 g
Price	$985.00

Description:

Physical Properties:

Off-white/white solid or viscous liquid depends on molecule weight;
Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

Store at -20 ⁰C, dessiccated Protect from light. Avoid frequent thaw and freeze.

Documents

SDS
DataSheet

DSPE PEG Maleimide, DSPE-PEG-MAL Cat. No. PG2-DSML-1k 1000 Da 100 mg修饰性聚乙二醇

发表于2023年9月18日由上海金畔生物科技有限公司

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DSPE PEG Maleimide, DSPE-PEG-MAL

Cat. No.	PG2-DSML-1k
Specification	1000 Da
Unit Size	100 mg
Price	$425.00

Synonym: Maleimide PEG DSPE, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine PEG Maleimide, DSPE-PEG-Mal.

Description:

Physical Properties:

Form: Solid powder;
Color: White;
Solubility: Soluble in chloroform and warm water;
Reactive group: Maleimide;
Reactive to: Sulfhydryl (-SH);
Lipid type: 18C PE, saturated;
Purity: >95%

Storage Conditions:

Store at -20 ⁰C. Avoid frequent thaw and freeze.

Documents

SDS
DataSheet

DOPE PEG, mPEG-DOPE Cat. No. PG1-DO-5k 5000 Da 50 mg修饰性聚乙二醇

发表于2023年9月18日由上海金畔生物科技有限公司

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DOPE PEG, mPEG-DOPE

Cat. No.	PG1-DO-5k
Specification	5000 Da
Unit Size	50 mg
Price	$485.00

Description:

1,2-Dioleoyl-sn-Glycero-3-Phosphoethanolamine (DOPE) conjugated Polyethylene Glycol, DOPE PEG is an unsaturated C18 phospholipid PEG conjugate which has both hydrophilicity and hydrophobility. Pegylated phospholipids are excellent liposome formation materials that can be used for drug delivery, gene transfection and vaccine delivery as well. Pegylation of phospholipids significantly improves the blood circulation time and stability for encapsulated drugs. These materials can also be used for targeted drug delivery by modifying their surfaces with targeting ligands such as antibodies, peptides.

Physical Properties:

Off-white/white solid or viscous liquid depends on molecule weight;
Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

Store at -20 ⁰C, dessiccated Protect from light. Avoid frequent thaw and freeze.

Documents

SDS
DataSheet

Thiol PEG, mPEG-SH Cat. No. PG1-TH-5k-1 5000 Da 1 g修饰性聚乙二醇

发表于2023年9月18日由上海金畔生物科技有限公司

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Thiol PEG, mPEG-SH

Cat. No.	PG1-TH-5k-1
Specification	5000 Da
Unit Size	1 g
Price	$325.00

Synonym: PEG thiol, mPEG-SH, HS-PEG, Polyethylene glycol thiol, mPEG5000 Thiol, Thiol PEG5000

Description:

Thiol functionalized methoxyl polyethylene glycol, PEG thiol (mPEG-SH) is one of Nanocs monofunctional PEG derivatives that can be used to modify proteins, peptides and other materials. Thiol groups also have high affinity to gold surface and are widely used for gold nanoparticles or gold film modification. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties:

Form: Solid
Color: White
Solubility: Soluble in water
Functional group: Thiol (-SH)
Purity: >95%
Applications: Surface modification, bioconjugation

Storage Conditions:

Store at -20 ⁰C. Avoid frequent thaw and freeze.

References:

Click here to see hundreds of publications using Nanocs PEGs

Documents

SDS
DataSheet

Polystyrene beads, streptavidin coated Cat. No. PS2u-SV-1 2 um 0.5 mL修饰性聚乙二醇

发表于2023年9月18日由上海金畔生物科技有限公司

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Polystyrene beads, streptavidin coated

Cat. No.	PS2u-SV-1
Specification	2 um
Unit Size	0.5 mL
Price	$385.00

Description:

Physical Properties:

1% suspension in aqueous solution, other concentration available upon request;

Storage Conditions:

Store at 4 ⁰C.

Azido PEG OPSS, N3-PEG-OPSS Cat. No. PG2-AZOS-3k 3400 Da 100 mg修饰性聚乙二醇

发表于2023年9月18日由上海金畔生物科技有限公司

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Azido PEG OPSS, N3-PEG-OPSS

Cat. No.	PG2-AZOS-3k
Specification	3400 Da
Unit Size	100 mg
Price	$385.00

Description:

Azide/azido functionalized polyethylene glycol (N3-PEG-X) is a bifunctional PEG derivative that can be used to modify proteins, peptides and other materials. Azide group can react with alkyne in aqueous solution catalyzed by copper. It can also be reduced into amine group easily while another functional group can be react with other molecules or functional groups. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties: