上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
NH2-PEG4-COOH
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- SDS
- DataSheet
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
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产品名称 | 二硬脂酰基磷脂酰乙醇胺 PEG 羧酸, DSPE-PEG-COOH |
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英文名称 | DSPE PEG Acid, DSPE-PEG-COOH |
规格或纯度 | MW 1000 Da |
运输条件 | 超低温冰袋运输 |
1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine (DSPE) conjμgated Polyethylene Glycol, DSPE PEG is a phospholipid PEG conjμgate which has both hydrophilicity and hydrophobility. Pegylated phospholipids are excellent liposome formation materials that can be used for drμg delivery, gene transfection and vaccine delivery as well. Pegylation of phospholipids significantly improves the blood circulation time and stability for encapsulated drμgs. These materials can also be used for targeted drμg delivery by modifying their surfaces with targeting ligands such as antibodies, peptides.
1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine (DSPE) conjugated Polyethylene Glycol, DSPE PEG is a phospholipid PEG conjugate which has both hydrophilicity and hydrophobility. Pegylated phospholipids are excellent liposome formation materials that can be used for drug delivery, gene transfection and vaccine delivery as well. Pegylation of phospholipids significantly improves the blood circulation time and stability for encapsulated drugs. These materials can also be used for targeted drug delivery by modifying their surfaces with targeting ligands such as antibodies, peptides.
溶解性 | Off-white/white solid or viscous liquid depends on molecule weight;Soluble in regular aqeous solution as well as most organic solvents; |
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储存温度 | -20°C储存 |
品牌 | Jinpan |
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
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上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
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产品名称 | 马来酰亚胺聚乙二醇羧酸,MAL-PEG-COOH |
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英文名称 | Maleimide PEG Acid, MAL-PEG-COOH |
别名 | 马来酰亚胺 PEG 羧酸, MAL-PEG-COOH |
规格或纯度 | 95%,MW 1000 Da |
运输条件 | 超低温冰袋运输 |
Maleimide PEG acid (Maleimide-PEG-COOH) is a thiol reactive heterobifunctional PEG derivative. Maleimide groups react with sulfhydryl groups at pH 6.5~7.5 at room temperature to form stable thioether bonds, while carboxylic acid groups on the other end can react with amine and acid amine reactive molecues.
Maleimide PEG acid (Maleimide-PEG-COOH) is a thiol reactive heterobifunctional PEG derivative. Maleimide groups react with sulfhydryl groups at pH 6.5~7.5 at room temperature to form stable thioether bonds, while carboxylic acid groups on the other end can react with amine and acid amine reactive molecues.
敏感性 | 对光线敏感 |
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溶解性 | Off-white/white solid or viscous liquid depends on molecule weight;Soluble in regular aqeous solution as well as most organic solvents; |
储存温度 | -20°C储存,充氩 |
品牌 | Jinpan |
产品名称 | mPEG-COOH |
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英文名称 | Carboxylic PEG acid, mPEG-COOH |
规格或纯度 | MW 1000 Da |
运输条件 | 超低温冰袋运输 |
Carboxylic acid functionalized methoxyl polyethylene glycol, PEG acid (mPEG-COOH) is a mono reactive PEG derivative that can be used to modify proteins, peptides and other materials via amino or other acid reactive chemical groups. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.
Carboxylic acid functionalized methoxyl polyethylene glycol, PEG acid (mPEG-COOH) is a mono reactive PEG derivative that can be used to modify proteins, peptides and other materials via amino or other acid reactive chemical groups. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.
敏感性 | 对光敏感 |
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溶解性 | Soluble in regular aqeous solution as well as most organic solvents; |
储存温度 | 避光,-20°C储存,充氩 |
品牌 | Jinpan |
上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
(S,R,S)-AHPC-PEG5-COOH (Synonyms: VH032-PEG5-COOH; VHL Ligand-Linker Conjugates 16; E3 Ligase Ligand-Linker Conjugates 58) 纯度: 95.01%
(S,R,S)-AHPC-PEG5-COOH (VH032-PEG5-COOH) 是一种合成的 E3 连接酶配体-linker 偶联物,包含基于 (S,R,S)-AHPC 的 VHL 配体和 5 个单元 PEG linker。
(S,R,S)-AHPC-PEG5-COOH Chemical Structure
CAS No. : 2172820-14-1
规格 | 价格 | 是否有货 | 数量 |
---|---|---|---|
10 mM * 1 mL in DMSO | ¥2090 | In-stock | |
25 mg | ¥1900 | In-stock | |
50 mg | ¥3200 | In-stock | |
100 mg | ¥5500 | In-stock | |
200 mg | 询价 | ||
500 mg | 询价 |
* Please select Quantity before adding items.
生物活性 |
(S,R,S)-AHPC-PEG5-COOH (VH032-PEG5-COOH) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 5-unit PEG linker used in PROTAC technology[1]. |
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IC50 & Target |
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分子量 |
750.90 |
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Formula |
C36H54N4O11S |
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CAS 号 |
2172820-14-1 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
-20°C, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen) |
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溶解性数据 |
In Vitro:
DMSO : ≥ 100 mg/mL (133.17 mM) * “≥” means soluble, but saturation unknown. 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |
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参考文献 |
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所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务
上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
Thalidomide-O-C8-COOH 纯度: 95.30%
Thalidomide-O-C8-COOH 是一种基于 Thalidomide 的,可募集 CRBN 蛋白的 Cereblon 配体。Thalidomide-O-C8-COOH 可通过 linker 与靶蛋白配体连接,形成 PROTAC 分子。
Thalidomide-O-C8-COOH Chemical Structure
CAS No. : 2225148-51-4
规格 | 价格 | 是否有货 | 数量 |
---|---|---|---|
100 mg | ¥6800 | In-stock | |
500 mg | ¥18000 | In-stock | |
1 g | 询价 | ||
5 g | 询价 |
* Please select Quantity before adding items.
生物活性 |
Thalidomide-O-C8-COOH is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-O-C8-COOH (Cereblon ligand 3) can be connected to the ligand for protein by a linker to form PROTACs[1]. |
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IC50 & Target |
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分子量 |
430.45 |
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Formula |
C22H26N2O7 |
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CAS 号 |
2225148-51-4 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
-20°C, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen) |
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溶解性数据 |
In Vitro:
DMSO : 140 mg/mL (325.24 mM; Need ultrasonic) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
*以上所有助溶剂都可在 上海金畔生物科技有限公司 网站选购。
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参考文献 |
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所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务
上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
EED226-COOH 纯度: 99.68%
EED226-COOH 是一种基于 EED226 的 PROTAC 靶蛋白 EED 配体,通过 linker 与 VHL 配体结合形成 PRC2 降解剂 UNC6852 (HY-130708)。
EED226-COOH Chemical Structure
CAS No. : 2467965-71-3
规格 | 价格 | 是否有货 | 数量 |
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Free Sample (0.1-0.5 mg) | Apply now | ||
10 mM * 1 mL in DMSO | ¥4950 | In-stock | |
10 mg | ¥4500 | In-stock | |
25 mg | ¥7500 | In-stock | |
50 mg | ¥13000 | In-stock | |
100 mg | ¥20000 | In-stock | |
200 mg | 询价 | ||
500 mg | 询价 |
* Please select Quantity before adding items.
生物活性 |
EED226-COOH is an EED226-derived ligand for target protein EED ligand for PROTAC, binds to a ligand for VHL via linker to form UNC6852 (HY-130708) to degrade PRC2[1]. |
IC50 & Target |
EED[1] |
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体外研究 (In Vitro) |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
335.32 |
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Formula |
C17H13N5O3 |
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CAS 号 |
2467965-71-3 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 |
In Vitro:
DMSO : 125 mg/mL (372.78 mM; Need ultrasonic) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
|
所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务
上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
Boc-C16-COOH
Boc-C16-COOH 是不可降解 (non-cleavable) 的 ADC linker,用于合成抗体偶联药物 (ADCs)。Boc-C16-COOH 也是一个基于烷基链 (alkyl chain) 的 PROTAC linker,可用于合成 PROTAC。
Boc-C16-COOH Chemical Structure
CAS No. : 843666-40-0
规格 | 价格 | 是否有货 | 数量 |
---|---|---|---|
50 mg | ¥1800 | In-stock | |
100 mg | ¥2700 | In-stock | |
250 mg | ¥4800 | In-stock | |
500 mg | 询价 | ||
1 g | 询价 |
* Please select Quantity before adding items.
生物活性 |
Boc-C16-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-C16-COOH is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1] |
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IC50 & Target |
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体外研究 (In Vitro) |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
370.57 |
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Formula |
C22H42O4 |
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CAS 号 |
843666-40-0 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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参考文献 |
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所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
|
上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
Thalidomide-PEG3-COOH 纯度: 98.05%
Thalidomide-PEG3-COOH 是一种合成的 E3 连接酶配体-linker 偶联物,包含基于 Thalidomide 的 cereblon 配体和 1 个 linker。
Thalidomide-PEG3-COOH Chemical Structure
规格 | 价格 | 是否有货 | 数量 |
---|---|---|---|
100 mg | ¥10000 | In-stock | |
200 mg | 询价 | ||
500 mg | 询价 |
* Please select Quantity before adding items.
生物活性 |
Thalidomide-PEG3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. |
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IC50 & Target |
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体外研究 (In Vitro) |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
434.40 |
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Formula |
C20H22N2O9 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
-20°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
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溶解性数据 |
In Vitro:
DMSO : 250 mg/mL (575.51 mM; Need ultrasonic) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
|
所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
|
上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
Pomalidomide-PEG2-COOH (Synonyms: Pomalidomide 4′-PEG2-acid) 纯度: 99.87%
Pomalidomide-PEG2-COOH (Pomalidomide 4′-PEG2-acid) 是一种合成的 E3 连接酶配体-linker 偶联物,它包含基于 Pomalidomide 的 cereblon 配体和连接子。Pomalidomide-PEG2-COOH 可用于 PROTAC 合成。
Pomalidomide-PEG2-COOH Chemical Structure
CAS No. : 2140807-17-4
规格 | 价格 | 是否有货 | 数量 |
---|---|---|---|
25 mg | ¥1580 | In-stock | |
50 mg | ¥3200 | In-stock | |
100 mg | 询价 | ||
200 mg | 询价 |
* Please select Quantity before adding items.
生物活性 |
Pomalidomide-PEG2-COOH (Pomalidomide 4′-PEG2-acid) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1]. |
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体外研究 (In Vitro) |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
433.41 |
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Formula |
C20H23N3O8 |
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CAS 号 |
2140807-17-4 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
4°C, stored under nitrogen, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture) |
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溶解性数据 |
In Vitro:
DMSO : 250 mg/mL (576.82 mM; Need ultrasonic) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
|
所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务
上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
OPSS-PEG8-COOH
OPSS-PEG8-COOH 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。
OPSS-PEG8-COOH Chemical Structure
CAS No. : 1334177-96-6
规格 | 是否有货 | ||
---|---|---|---|
100 mg | 询价 | ||
250 mg | 询价 | ||
500 mg | 询价 |
* Please select Quantity before adding items.
生物活性 |
OPSS-PEG8-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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IC50 & Target |
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体外研究 (In Vitro) |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
638.79 |
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Formula |
C27H46N2O11S2 |
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CAS 号 |
1334177-96-6 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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参考文献 |
|
所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务
上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
Thalidomide-PEG5-COOH 纯度: 98.09%
Thalidomide-PEG5-COOH 是一种合成的 E3 连接酶配体-linker 偶联物,包含基于 Thalidomide 的 cereblon 配体和 1 个 linker。
Thalidomide-PEG5-COOH Chemical Structure
规格 | 价格 | 是否有货 | 数量 |
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100 mg | ¥15000 | In-stock | |
200 mg | 询价 | ||
500 mg | 询价 |
* Please select Quantity before adding items.
生物活性 |
Thalidomide-PEG5-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. |
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IC50 & Target |
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体外研究 (In Vitro) |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
522.50 |
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Formula |
C24H30N2O11 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
-20°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
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溶解性数据 |
In Vitro:
DMSO : 50 mg/mL (95.69 mM; Need ultrasonic) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务
上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
Thalidomide-PEG4-COOH 纯度: 95.08%
Thalidomide-PEG4-COOH 是一种合成的 E3 连接酶配体-linker 偶联物,包含基于 Thalidomide 的 cereblon 配体和 1 个 linker。
Thalidomide-PEG4-COOH Chemical Structure
规格 | 价格 | 是否有货 | 数量 |
---|---|---|---|
100 mg | ¥10000 | In-stock | |
200 mg | 询价 | ||
500 mg | 询价 |
* Please select Quantity before adding items.
生物活性 |
Thalidomide-PEG4-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. |
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IC50 & Target |
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体外研究 (In Vitro) |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
478.45 |
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Formula |
C22H26N2O10 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
-20°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
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溶解性数据 |
In Vitro:
DMSO : 250 mg/mL (522.52 mM; Need ultrasonic) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务
上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
Apalutamide-COOH
Apalutamide-COOH 是 Apalutamide 的代谢物。Apalutamide 是有效,竞争性的雄激素受体 (AR) 拮抗剂,IC50 为 16 nM。
Apalutamide-COOH Chemical Structure
CAS No. : 1332391-04-4
规格 | 价格 | 是否有货 | |
---|---|---|---|
5 mg | ¥3500 | 询问价格 & 货期 | |
10 mg | ¥5500 | 询问价格 & 货期 |
* Please select Quantity before adding items.
生物活性 |
Apalutamide-COOH is a metabolite of Apalutamide. Apalutamide is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM[1]. |
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分子量 |
464.39 |
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Formula |
C20H12F4N4O3S |
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CAS 号 |
1332391-04-4 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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参考文献 |
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所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务
上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
KB02-COOH 纯度: 98.88%
KB02-COOH 是泛素 E3 连接酶配体 KB02 的合成片段。KB02 可用于 PROTAC 的合成,例如 KB02-JQ1 (HY-129917) 和 KB02-SLF (HY-129610)。
KB02-COOH Chemical Structure
CAS No. : 2375196-30-6
规格 | 价格 | 是否有货 | 数量 |
---|---|---|---|
10 mM * 1 mL in DMSO | ¥3300 | In-stock | |
5 mg | ¥3000 | In-stock | |
10 mg | ¥4800 | In-stock | |
50 mg | ¥14500 | In-stock | |
100 mg | ¥22500 | In-stock | |
200 mg | 询价 | ||
500 mg | 询价 |
* Please select Quantity before adding items.
生物活性 |
KB02-COOH is a fragment of synthesis of ubiquitin E3 ligase ligand KB02. KB02 can be used in the synthesis of PROTAC, such as KB02-JQ1 (HY-129917) and KB02-SLF (HY-129610)[1]. |
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IC50 & Target[1] |
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分子量 |
283.71 |
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Formula |
C13H14ClNO4 |
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CAS 号 |
2375196-30-6 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 |
In Vitro:
DMSO : 66.67 mg/mL (234.99 mM; Need ultrasonic) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
|
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参考文献 |
|
所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务
上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
Thiol-PEG-COOH (MW 5000)
Thiol-PEG-COOH (MW 5000) 是一种 PROTAC linker,属于 PEG 类。Boc-NH-C6-amido-C4-acid 可用于合成 PROTAC 分子。
Thiol-PEG-COOH (MW 5000) Chemical Structure
规格 | 是否有货 | ||
---|---|---|---|
100 mg | 询价 | ||
250 mg | 询价 | ||
500 mg | 询价 |
* Please select Quantity before adding items.
生物活性 |
Thiol-PEG-COOH (MW 5000) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
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IC50 & Target |
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体外研究 (In Vitro) |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
5000(Average) |
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Formula |
C11H21NO5S |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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参考文献 |
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所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务