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Ethyl Orsellinate (Synonyms: 山梨酸乙酯)
Ethyl Orsellinate 是地衣代谢产物，lecanoric acid 的衍生物，具有抗增殖和抗肿瘤活性。Ethyl Orsellinate 抑制 A.salina 的细胞毒性活性，LC50 为 495 μM。
Ethyl Orsellinate Chemical Structure
CAS No. : 2524-37-0
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| 生物活性 |
Ethyl orsellinate is a lichen metabolite and a derivative of lecanoric acid with antiproliferative and antitumour activities[1]. Ethyl Orsellinate is against A. salina for the cytotoxic activity with an LC50 of 495 μM[2]. |
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| 体外研究 (In Vitro) |
Ethyl Orsellinate (0-50 μg/ml; 48 hours) inhibits Hep-2 cells, MCF-7 breast cancer cells, and 786-0 kidney carcinoma cells, as well as B16-F10 murine melanoma and non-cancerous Vero cells (IC50s=31.2, 70.3, 47.5, 64.8, and 28.1 µg/ml, respectively)[2]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 分子量 |
196.20 |
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| Formula |
C10H12O4 |
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| CAS 号 |
2524-37-0 |
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| 中文名称 |
山梨酸乙酯 |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
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