Lipoic acid PEG Aminooxy

Synonym: Aminooxy PEG Lipoic acid, Oxyamine PEG Lipoic acid, Hydroxyamine PEG Lipoic acid, Lipoic acid-PEG-ONH2.

Description:

Lipoic acid PEG Aminooxy (Lipoic acid-PEG-ONH2) is one of Nanocs carbonyl reactive PEG derivatives that have a lipoic acid group on one end of PEG and an aminooxy group (-ONH2) on the other terminus. Lipoic acid, also known as thioctic acid, contains a disufide bond that can bind to gold and other metal surface. It is also an important molecule parting in various biological processes. Aminooxy group (-ONH2), on the other hand, can react with aldehyde or ketone groups derived from polysaccarides or glycoproteins. Reaction between aminooxy and ketone group results in a stable oxime linkage, which is more stable than the schiff base formed between amine and ketone group. 

Product Specification:

• Form: Solid powder or semi-solid depends on PEG length
• Color: Yellow to pale yellow
• Reactive group: Aminooxy (-ONH2)
• Reactive to: Aldehyde/ketone
• Solubility: Soluble in water

Storage Conditions:

• Store at -20 ⁰C. 

Lipoic acid PEG azide, LA-PEG-N3

Description:

Lipoic acid PEG azide is one of Nanocs’ surface reactive PEG derivatives that have a lipoic acid moiety on one PEG terminus and an azide group on the other PEG end. Lipoic acid, also known as thioctic acid, is an important bioactive molecule participating in various biological processes. PEG functionalized lipoic acid can be used to bind to metallic particle or film surface with its disulfide bond. Lipoic acid group has high affinity to metallic surfaces and have been widely used for gold nanoparticles and quantum dots surface modification. Azide group can react with linear alkye or strain-promoted cyclooctyne through so called Click Chemistry. PEGylated lipoic acid azide is water soluble and can be used directly in aqueous buffer.

Physical Properties:

• Off-yellow solid.
• Soluble in regular aqeous solution as well as most organic solvents;
• Reactive group: Azide (-N3):
• Reactive toward: Alkyne;

Storage Conditions:

• Store at -20 ⁰C.

Lipoic acid PEG Maleimide, LA-PEG-Mal

Description:

Lipoic acid, also known as thioctic acid, is an important bioactive molecule participating in various biological processes. PEG functionalized lipoic acid can be used to bind to metallic particle or film surface with its -S-S-bond. Lipoic acid group has high affinity to metallic surfaces and have been widely used for gold nanoparticles and quantum dots surfaces. PEGylated lipoic acid is water soluble and can be used directly in aqueous buffer.

Physical Properties:

• Off-yellow solid or viscous liquid depends on molecule weight;
• Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

• Store at -20 ⁰C, dessiccated Protect from light. Avoid frequent thaw and freeze.

Lipoic acid PEG azide, LA-PEG-N3

Description:

Lipoic acid PEG azide is one of Nanocs’ surface reactive PEG derivatives that have a lipoic acid moiety on one PEG terminus and an azide group on the other PEG end. Lipoic acid, also known as thioctic acid, is an important bioactive molecule participating in various biological processes. PEG functionalized lipoic acid can be used to bind to metallic particle or film surface with its disulfide bond. Lipoic acid group has high affinity to metallic surfaces and have been widely used for gold nanoparticles and quantum dots surface modification. Azide group can react with linear alkye or strain-promoted cyclooctyne through so called Click Chemistry. PEGylated lipoic acid azide is water soluble and can be used directly in aqueous buffer.

Physical Properties:

• Off-yellow solid.
• Soluble in regular aqeous solution as well as most organic solvents;
• Reactive group: Azide (-N3):
• Reactive toward: Alkyne;

Storage Conditions:

• Store at -20 ⁰C.

Lipoic acid PEG acid, LA-PEG-COOH

Description:

Lipoic acid, also known as thioctic acid, is an important bioactive molecule participating in various biological processes. PEG functionalized lipoic acid can be used to bind to metallic particle or film surface with its -S-S-bond. Lipoic acid group has high affinity to metallic surfaces and have been widely used for gold nanoparticles and quantum dots surfaces. PEGylated lipoic acid is water soluble and can be used directly in aqueous buffer.

Physical Properties:

• Off-yellow solid or viscous liquid depends on molecule weight;
• Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

• Store at -20 ⁰C, dessiccated Protect from light. Avoid frequent thaw and freeze.

Lipoic acid PEG acid, LA-PEG-COOH

Description:

Lipoic acid, also known as thioctic acid, is an important bioactive molecule participating in various biological processes. PEG functionalized lipoic acid can be used to bind to metallic particle or film surface with its -S-S-bond. Lipoic acid group has high affinity to metallic surfaces and have been widely used for gold nanoparticles and quantum dots surfaces. PEGylated lipoic acid is water soluble and can be used directly in aqueous buffer.

Physical Properties:

• Off-yellow solid or viscous liquid depends on molecule weight;
• Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

• Store at -20 ⁰C, dessiccated Protect from light. Avoid frequent thaw and freeze.

Lipoic acid PEG acid, LA-PEG-COOH

Description:

Lipoic acid, also known as thioctic acid, is an important bioactive molecule participating in various biological processes. PEG functionalized lipoic acid can be used to bind to metallic particle or film surface with its -S-S-bond. Lipoic acid group has high affinity to metallic surfaces and have been widely used for gold nanoparticles and quantum dots surfaces. PEGylated lipoic acid is water soluble and can be used directly in aqueous buffer.

Physical Properties:

• Off-yellow solid or viscous liquid depends on molecule weight;
• Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

• Store at -20 ⁰C, dessiccated Protect from light. Avoid frequent thaw and freeze.

Lipoic acid PEG COOH

Synonym: Lipoic acid PEG acid, LA-PEG-COOH, COOH-PEG-Lipoic acid, Thioctic acid PEG COOH.

Description:

Lipoic acid PEG COOH is one of Nanocs' reactive Lipoic acid PEG derivatives that have a lipoic acid on one PEG terminus and a carboxylic acid (COOH) on the other PEG end. Lipoic acid, also known as thioctic acid, is an important bioactive molecule participating in various biological processes. It is also a good metal chelator. Carboxyl functionalized lipoic acid PEG allows the attachment of lipoic acid to other molecules and materials through reaction between COOH and other functional groups. PEG linker bridged lipoic acid and COOH group offers better water solubility, flexible spacer length and minimal non-specific binding.

Product Specifications:

• Composition: Lipoic acid PEG COOH
• Appearance: Pale-yellow, off-white semi-solid to solid depends on MW of PEG
• Solubility: Soluble in water
• Functional group: Lipoic acid
• Reactive group: Carboxylic acid (-COOH)
• Reactive to: Amine (-NH2), Hydroxyl (-OH)

Storage:

• Lipoic acid PEG COOH should be stored 4 ⁰C or lower. 

Lipoic acid PEG Hydrazide

Synonym: Hydrazide PEG Lipoic acid,  Lipoic acid-PEG-CONHNH2, LPA-PEG-CONHNH2.

Description:

Lipoic acid PEG Hydrazide (Lipoic acid-PEG-CONHNH2) is one of Nanocs carbonyl reactive PEG derivatives that have a lipoic acid group on one end of PEG and a hydrazide group (-NHNH2) on the other terminus. Lipoic acid, also known as thioctic acid, contains a disufide bond that can bind to gold and other metal surface. It is also an important molecule parting in various biological processes. Hydrazide group (-NHNH2), on the other hand, can react with aldehyde or ketone groups derived from polysaccarides or glycoproteins. Reaction between hydrazide and ketone group results in a stable hydrazone bond, which is more stable than the schiff base formed between amine and ketone group. 

Product Specification:

• Form: Solid powder or semi-solid depends on PEG length
• Color: Yellow to pale yellow
• Reactive group: Hydrazide (-CONHNH2)
• Reactive to: Aldehyde/ketone
• Solubility: Soluble in water

Storage Conditions:

• Store at -20 ⁰C. 

Lipoic acid PEG Alkyne

Synonym: Alkyne PEG Lipoic acid,  Lipoic acid-PEG-Alkyne, LPA-PEG-Alkyne.

Description:

Lipoic acid PEG Alkyne (LPA-PEG-Alkyne) is one of Nanocs click chemistry reactive PEG derivatives that have a lipoic acid group on one end of PEG and an alkynde on the other terminus. Lipoic acid, also known as thioctic acid, contains a disufide bond that can bind to gold and other metal surface. It is also an important molecule parting in various biological processes. Alkyne, on the other hand, can react with azide group in aqueous solution via so called Click Chemistry.  Reaction between alkyne and azide results in a stable conjugation of Lipoic acid PEG to targeted substrates.

Product Specification:

• Form: Solid powder or semi-solid depends on PEG length
• Color: Yellow to pale yellow
• Reactive group: Alkyne
• Reactive to: Azide
• Solubility: Soluble in water

Storage Conditions:

• Store at -20 ⁰C. 

Lipoic acid PEG DBCO

Synonym: DBCO PEG Lipoic acid, LPA-PEG-DBCO.

Description:

Lipoic acid PEG DBCO is one of Nanocs Click Chemistry reactive PEG derivatives that have a lipoic acid group on one end of PEG chain and a DBCO group (Dibenzocyclooctyne) on the other PEG terminus. Lipoic acid, also known as thioctic acid, contains a disufide bond that can bind to gold and other metal surface. It is also an important molecule parting in various biological processes. DBCO, on the other hand, is able to react with azide group via so called copper-free click chemistry reaction. Reaction between DBCO and azide allows efficient conjugation of Lipoic acid to targeted molecules quickly and easily. 

Product Specification:

• Form: Solid powder or semi-solid depends on PEG length
• Color: Yellow to pale yellow
• Reactive group: DBCO
• Reactive to: Azide/Azido
• Solubility: Soluble in water

Storage Conditions:

• Store at -20 ⁰C. 

Lipoic acid PEG Cy5

Synonym: Thioctic acid PEG Cy5, Cy5 PEG Lipoic acid, LPA-PEG-Cy5.

Similar products: Lipoic acid PEG SF650, Alexa Fluor 647 PEG Lipoic acid

Description:

Lipoic acid PEG Cy5 is one of Nanocs fluorescent PEG derivatives that have a lipoic acid group on one end of PEG chain and a Cy5 fluorescent dye on the other PEG terminus. Lipoic acid, also known as thioctic acid, contains a disufide bond that can bind to gold and other metal surface. It is also an important molecule parting in various biological processes. Cy5, on the other hand, is a bright cyanine dye that has excitation/emission wavelength at 650 nm/670 nm. Cy5 labeled lipoic acid PEG can be easily detected with common fluorescent instruments.

Product Specification:

• Form: Solid powder or semi-solid depends on PEG length
• Color: Blue or dark blue
• Fluorescent dye: Cy5
• Ex/Em: 650 nm/670 nm
• Solubility: Soluble in water

Storage Conditions:

• Store at -20 ⁰C. Protect from light.